Schultz B K, Palmieri C, Nicolson V, Larkin R, Keeley T, McGowan M, Johnston S D
Wildlife Science Unit, School of Agriculture and Food Science, The University of Queensland, Gatton 4343, Australia; School of Veterinary Science, The University of Queensland, Gatton 4343, Australia.
School of Veterinary Science, The University of Queensland, Gatton 4343, Australia.
Res Vet Sci. 2016 Aug;107:30-33. doi: 10.1016/j.rvsc.2016.05.002. Epub 2016 May 10.
This study reports the first documented clinical case of a spermatic granuloma and varicocele in a marsupial. Initial clinical presentation included gross morphological changes in the left scrotal cord, epididymis and testis. Ultrasonography of the scrotum and spermatic cord, and gross and histopathological examination after hemicastration, confirmed the condition as a spermatic granuloma affecting the left caput epididymis, with a varicocele in the left proximal spermatic cord, which was causing azoospermia and infertility. Semen quality and serum testosterone secretion following a GnRH challenge was assessed prior to, and following surgery. After hemi-castration, an increase in androgen secretion to within normal reference ranges for the koala was observed with a subsequent increase in semen production and sperm quality resulting in the sire of a pouch young, 12months later.
本研究报告了有袋动物中首例有记录的精索肉芽肿和精索静脉曲张临床病例。最初的临床表现包括左侧阴囊索、附睾和睾丸的明显形态变化。阴囊和精索的超声检查，以及半侧睾丸切除术后的大体和组织病理学检查，证实该病症为影响左侧附睾头的精索肉芽肿，左侧精索近端有精索静脉曲张，导致无精子症和不育。在手术前后评估了GnRH刺激后精液质量和血清睾酮分泌情况。半侧睾丸切除术后，观察到雄激素分泌增加至考拉正常参考范围内，随后精液产量和精子质量增加，12个月后产下一只育儿袋幼崽。
