DeLay Kenneth Jackson, McVary Kevin T
Department of Urology, Tulane University Health Sciences Center, New Orleans, LA, USA.
Division of Urology, Southern Illinois University School of Medicine, 301 North 8th Street, St John's Pavilion, PO Box 19665, Springfield, IL 62794, USA.
Urol Clin North Am. 2016 Aug;43(3):371-5. doi: 10.1016/j.ucl.2016.04.005.
Benign prostatic hyperplasia (BPH) refers to proliferation of smooth muscle and epithelial cells within the transition zone of the prostate. Half of men over 40 develop histologic BPH. About half of men with BPH develop an enlarged prostate gland, called benign prostatic enlargement; among these, about half develop some degree of bladder outlet obstruction. Bladder outlet obstruction and changes in smooth muscle tone and resistance may result in lower urinary tract symptoms, including storage disturbances (such as daytime urinary urgency, frequency, and nocturia) and voiding disturbances (such as urinary hesitancy, weak urinary stream, straining to void, and prolonged voiding).
良性前列腺增生(BPH)是指前列腺移行区内平滑肌和上皮细胞的增生。40岁以上的男性中,有一半会出现组织学上的良性前列腺增生。大约一半的良性前列腺增生患者会出现前列腺肿大,称为良性前列腺肥大;在这些患者中,约一半会出现一定程度的膀胱出口梗阻。膀胱出口梗阻以及平滑肌张力和阻力的变化可能导致下尿路症状,包括储尿障碍(如白天尿急、尿频和夜尿症)和排尿障碍(如排尿犹豫、尿流无力、用力排尿和排尿时间延长)。