Ilyas Imran, Alrumaih Husam, Rabbani Samar
Department of Orthopedic Surgery, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia; Associate Professor at Alfaisal University, College of Medicine, Riyadh, Saudi Arabia.
Department of Orthopedic Surgery, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
J Arthroplasty. 2017 Jan;32(1):171-176. doi: 10.1016/j.arth.2016.06.016. Epub 2016 Jun 22.
Femoral bone deficiency is a challenging problem in revision femoral arthroplasty in younger patients. We evaluated outcomes of revision femoral arthroplasty using a freeze-dried allograft prosthetic composite (APC).
This was a retrospective review of 16 patients (12 men and 4 women) who had unilateral proximal femoral deficiencies (Paprosky type III B, 13 patients; type IV, 3 patients) revised with freeze-dried APC. Follow-up at mean 7 years included assessment with Merle D'Aubigné score and radiographs.
At follow-up, the average hip score was improved for pain, function, and range of motion. The 5-year graft survival was 87%, and the estimated median survival was 8.8 years. There were 3 patients who walked without support, 10 patients who walked unlimited distance with a cane, 2 patients who walked with 2 crutches, and 1 patient who walked with a walker. Radiographs showed nonunion at the graft-host junction in 3 hips (19%), but only 1 patient was symptomatic. Asymptomatic trochanteric nonunion was observed in 4 hips (25%). There was moderate graft resorption in 2 patients at 9 years after surgery and mild graft resorption in 1 graft at 7 years. There was subsidence of <2 cm in 2 patients and 3.5 cm in 1 patient.
The present study showed acceptable results in treatment of major femoral deficiencies using freeze-dried APC in younger patients. Freeze-dried APC may be a useful for revision femoral arthroplasty.
股骨骨缺损是年轻患者股骨翻修置换术中一个具有挑战性的问题。我们评估了使用冻干同种异体骨假体复合物(APC)进行股骨翻修置换术的效果。
这是一项对16例患者(12例男性和4例女性)的回顾性研究,这些患者均有单侧股骨近端缺损(帕罗茨基III B型,13例;IV型,3例),采用冻干APC进行翻修。平均7年的随访包括使用梅里尔·达布尼评分和X线片进行评估。
随访时,髋关节的平均疼痛、功能和活动范围评分均有所改善。5年移植物存活率为87%,估计中位生存期为8.8年。3例患者无需支撑即可行走,10例患者使用拐杖可无限制行走,2例患者使用双拐行走,1例患者使用助行器行走。X线片显示3个股骨(19%)的移植物与宿主交界处未愈合,但只有1例患者有症状。4个股骨(25%)观察到无症状的转子不愈合。术后9年有2例患者出现中度移植物吸收,1例移植物在7年时出现轻度吸收。2例患者出现小于2 cm的下沉,1例患者出现3.5 cm的下沉。
本研究表明,在年轻患者中使用冻干APC治疗严重股骨缺损可取得可接受的结果。冻干APC可能对股骨翻修置换术有用。