Hari R, Joutsiniemi S L, Hämäläinen M, Vilkman V
Low Temperature Laboratory, Helsinki University of Technology, Espoo, Finland.
Neurosci Lett. 1989 Apr 24;99(1-2):164-8. doi: 10.1016/0304-3940(89)90283-8.
We have recorded, with a 7-channel SQUID gradiometer, evoked magnetic responses of 6 healthy humans to interruptions of a steady rhythm of 50 ms 'standard' tone bursts repeated once every 610 ms. Ten percent of the tones occurred 'too early', 410 ms after the preceding stimulus. The response to standards peaked, on average, at 90 ms and that to the early tones at 148 ms. Field patterns were dipolar during both responses and the equivalent sources agreed with activation of the supratemporal auditory cortex, at slightly different locations. The dipole moments were more than twice as strong for the early tones as for the standards. The results emphasize the importance of temporal stimulation patterns in activating the human auditory cortex.
我们使用7通道超导量子干涉仪梯度计记录了6名健康人类对以610毫秒重复一次的50毫秒“标准”音调脉冲串的稳定节奏被打断时的诱发磁反应。10%的音调出现得“过早”，在前一个刺激后410毫秒出现。对标准音调的反应平均在90毫秒达到峰值，对早发音调的反应在148毫秒达到峰值。在两种反应过程中，场模式均为偶极子模式，等效源与颞上听觉皮层的激活一致，但位置略有不同。早发音调的偶极矩强度是标准音调的两倍多。结果强调了时间刺激模式在激活人类听觉皮层中的重要性。
