单侧去皮质对基底核乙酰胆碱释放的影响。
Effect of unilateral decortication on acetylcholine release from the nucleus basalis.
作者信息
Boegman R J, Metcalf R H
机构信息
Department of Pharmacology and Toxicology, Queen's University, Kingston, Ont., Canada.
出版信息
Neurosci Lett. 1989 Apr 24;99(1-2):219-22. doi: 10.1016/0304-3940(89)90293-0.
PMID:2748015
Abstract
Acetylcholine (ACh) is released from the rat nucleus basalis magnocellularis (nbM) following tissue depolarization with 35 mM K+. In the present study, we report that cholinergic neurons within the nbM undergo retrograde changes resulting in a significant reduction in K+-evoked ACh release following cortical lesions.
摘要
用35 mM钾离子使组织去极化后，乙酰胆碱（ACh）从大鼠基底前脑大细胞基底核（nbM）释放。在本研究中，我们报告称，nbM内的胆碱能神经元会发生逆行性变化，导致皮质损伤后钾离子诱发的ACh释放显著减少。
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