Meyer F U, Becker I
Stomatol DDR. 1978 Feb;28(2):119-23.
In case of unintentional intravascular uptake, the injection of repository penicillin may produce severe embolic obturations. Several batches of respository penicillin were tested for their crystal size in ready-for-injection suspensions. The greatest crystals were found in preparations with a high proportion of benzylpenicillin-procaine. To avoid untoward reactions (Hoigné syndrome, Nicolau syndrome), the recommendations of the Central Expert Committe on Drugs must be considered. Furthermore, the measures required in case of anaphylactic shock are dealt with.
万一无意发生血管内摄取，长效青霉素注射可能会产生严重的栓塞阻塞。对几批注射用长效青霉素悬浮液的晶体大小进行了测试。在苄星青霉素-普鲁卡因比例高的制剂中发现了最大的晶体。为避免不良反应（霍伊内综合征、尼科劳综合征），必须考虑中央药物专家委员会的建议。此外，还讨论了过敏性休克时所需采取的措施。
