Alsharaa Abdulnaser, Sajid Muhammad, Basheer Chanbasha, Alhooshani Khalid, Lee Hian Kee
Department of Chemistry, King Fahd University of Petroleum and minerals, Dhahran, Saudi Arabia.
Department of Chemistry, National University of Singapore, Singapore.
J Sep Sci. 2016 Sep;39(18):3610-5. doi: 10.1002/jssc.201600305.
In the present study, highly efficient and simple dispersive solid-phase extraction procedure for the determination of haloacetic acids in water samples has been established. Three different types of layered double hydroxides were synthesized and used as a sorbent in dispersive solid-phase extraction. Due to the interesting behavior of layered double hydroxides in an acidic medium (pH˂4), the analyte elution step was not needed; the layered double hydroxides are simply dissolved in acid immediately after extraction to release the analytes which are then directly introduced into a liquid chromatography with tandem mass spectrometry system for analysis. Several dispersive solid-phase extraction parameters were optimized to increase the extraction efficiency of haloacetic acids such as temperature, extraction time and pH. Under optimum conditions, good linearity was achieved over the concentration range of 0.05-100 μg/L with detection limits in the range of 0.006-0.05 μg/L. The relative standard deviations were 0.33-3.64% (n = 6). The proposed method was applied to different water samples collected from a drinking water plant to determine the concentrations of haloacetic acids.
在本研究中，建立了一种高效且简单的分散固相萃取方法用于测定水样中的卤乙酸。合成了三种不同类型的层状双氢氧化物，并将其用作分散固相萃取中的吸附剂。由于层状双氢氧化物在酸性介质（pH˂4）中的有趣行为，不需要进行分析物洗脱步骤；萃取后，层状双氢氧化物只需简单地溶解在酸中以释放分析物，然后直接将其引入液相色谱-串联质谱系统进行分析。优化了几个分散固相萃取参数以提高卤乙酸的萃取效率，如温度、萃取时间和pH。在最佳条件下，在0.05-100μg/L的浓度范围内实现了良好的线性，检测限在0.006-0.05μg/L范围内。相对标准偏差为0.33-3.64%（n = 6）。所提出的方法应用于从饮用水厂采集的不同水样，以测定卤乙酸的浓度。
