一名老年患者上肢弥漫性大B细胞淋巴瘤酷似软组织肉瘤的罕见病例。
A rare case of the upper extremity diffuse large B-cell lymphoma mimicking soft tissue sarcoma in an elderly patient.
作者信息
Mamorska-Dyga Aleksandra, Ronny Faisal M H, Puccio Carmelo, Islam Humayun, Liu Delong
机构信息
1 Department of Medicine, 2 Department of Pathology, New York Medical College and Westchester Medical Center, Valhalla, NY, USA.
出版信息
Stem Cell Investig. 2016 Jun 24;3:25. doi: 10.21037/sci.2016.06.06. eCollection 2016.
Abstract
Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma, with about 30% of new cases presenting with extranodal disease. Lesions originating from soft tissues of the upper extremities are extremely rare and may mimic other malignancies like sarcoma. We present a case of an elderly patient with right upper extremity (RUE) mass which was proven to be DLBCL instead of sarcoma. We emphasize the increasing need for investigating new therapeutic options for patients of extreme age and/or with underlying heart disease.
摘要
弥漫性大B细胞淋巴瘤（DLBCL）是最常见的非霍奇金淋巴瘤类型，约30%的新发病例表现为结外病变。起源于上肢软组织的病变极为罕见，可能类似肉瘤等其他恶性肿瘤。我们报告一例老年患者，其右上肢肿块经证实为DLBCL而非肉瘤。我们强调，对于高龄和/或患有基础心脏病的患者，越来越需要探索新的治疗选择。
相似文献
1
A rare case of the upper extremity diffuse large B-cell lymphoma mimicking soft tissue sarcoma in an elderly patient.
Stem Cell Investig. 2016 Jun 24;3:25. doi: 10.21037/sci.2016.06.06. eCollection 2016.
2
Diffuse Large B-Cell Lymphoma of the Left Upper Extremity Mimicking a Sarcoma.
Cureus. 2021 Jun 11;13(6):e15588. doi: 10.7759/cureus.15588. eCollection 2021 Jun.
3
Extranodal lymphoma originating in the gluteal muscle with adjacent bone involvement and mimicking a soft tissue sarcoma.
Int J Surg Case Rep. 2015;7C:161-4. doi: 10.1016/j.ijscr.2015.01.024. Epub 2015 Jan 15.
4
Extranodal Diffuse Large B-Cell Lymphoma of Bone and Soft Tissue Presenting With Marked Lymphedema and Hypercalcemia.
Cureus. 2022 Feb 8;14(2):e22025. doi: 10.7759/cureus.22025. eCollection 2022 Feb.
5
Epstein-Barr virus-positive diffuse large B-cell lymphoma in children: a disease reminiscent of Epstein-Barr virus-positive diffuse large B-cell lymphoma of the elderly.
Hum Pathol. 2015 May;46(5):716-24. doi: 10.1016/j.humpath.2015.01.011. Epub 2015 Feb 3.
6
B-cell lymphoma presenting as multiple nerve sheath tumors.
Surg Neurol Int. 2017 Jul 11;8:142. doi: 10.4103/sni.sni_60_17. eCollection 2017.
7
A reassessment of primary thyroid lymphoma: high-grade MALT-type lymphoma as a distinct subtype of diffuse large B-cell lymphoma.
Histopathology. 2000 Jul;37(1):10-8. doi: 10.1046/j.1365-2559.2000.00941.x.
8
Diffuse large B-cell lymphoma.
Pathology. 2018 Jan;50(1):74-87. doi: 10.1016/j.pathol.2017.09.006. Epub 2017 Nov 20.
9
Primary Gastric EBV-positive Diffuse Large B Cell Lymphoma (DLBCL) of the Elderly with Plasmablastic Differentiation.
In Vivo. 2018 Mar-Apr;32(2):413-417. doi: 10.21873/invivo.11255.
10
Fast-Growing Subcutaneous Tumors with Lower-Extremity Edema and Rib Lesions: A Case of Non-Hodgkin's Lymphoma in an HIV-1-Infected Patient.
Am J Case Rep. 2017 Oct 25;18:1135-1139. doi: 10.12659/ajcr.905904.
引用本文的文献
1
Diffuse Large B-Cell Lymphoma of the Left Upper Extremity Mimicking a Sarcoma.
Cureus. 2021 Jun 11;13(6):e15588. doi: 10.7759/cureus.15588. eCollection 2021 Jun.
2
Diagnosis and treatment of CD20 negative B cell lymphomas.
Biomark Res. 2017 Feb 7;5:5. doi: 10.1186/s40364-017-0088-5. eCollection 2017.
本文引用的文献
1
Acalabrutinib (ACP-196) in Relapsed Chronic Lymphocytic Leukemia.
N Engl J Med. 2016 Jan 28;374(4):323-32. doi: 10.1056/NEJMoa1509981. Epub 2015 Dec 7.
2
ABT-199 (venetoclax) and BCL-2 inhibitors in clinical development.
J Hematol Oncol. 2015 Nov 20;8:129. doi: 10.1186/s13045-015-0224-3.
3
The isolated extranodal relapse of the isolated extranodal non- Hodgkin lymphoma: A case report.
J Cancer Res Ther. 2015 Jul-Sep;11(3):645. doi: 10.4103/0973-1482.147706.
4
Blinatumomab: a bispecific T cell engager (BiTE) antibody against CD19/CD3 for refractory acute lymphoid leukemia.
J Hematol Oncol. 2015 Sep 4;8:104. doi: 10.1186/s13045-015-0195-4.
5
AFM13: a first-in-class tetravalent bispecific anti-CD30/CD16A antibody for NK cell-mediated immunotherapy.
J Hematol Oncol. 2015 Aug 1;8:96. doi: 10.1186/s13045-015-0188-3.
6
Nonpegylated Liposomal Doxorubicin as a Component of R-CHOP Is an Effective and Safe Alternative to Conventional Doxorubicin in the Treatment of Patients With Diffuse Large B-Cell Lymphoma and Preexisting Cardiac Diseases.
Clin Lymphoma Myeloma Leuk. 2015 Aug;15(8):458-63. doi: 10.1016/j.clml.2015.03.008. Epub 2015 Mar 24.
7
Selective inhibitors of nuclear export (SINE) in hematological malignancies.
Exp Hematol Oncol. 2015 Mar 1;4:7. doi: 10.1186/s40164-015-0002-5. eCollection 2015.
8
Long-term follow-up of dose-adjusted EPOCH plus rituximab (DA-EPOCH-R) in untreated patients with poor prognosis large B-cell lymphoma. A phase II study conducted by the Spanish PETHEMA Group.
Br J Haematol. 2015 Apr;169(2):188-98. doi: 10.1111/bjh.13273. Epub 2014 Dec 18.
9
Pegylated liposomal doxorubicin replacing conventional doxorubicin in standard R-CHOP chemotherapy for elderly patients with diffuse large B-cell lymphoma: an open label, single arm, phase II trial.
Clin Lymphoma Myeloma Leuk. 2015 Mar;15(3):152-8. doi: 10.1016/j.clml.2014.09.001. Epub 2014 Sep 28.
10
Ibrutinib for B cell malignancies.
Exp Hematol Oncol. 2014 Jan 28;3(1):4. doi: 10.1186/2162-3619-3-4.
Zotero 插件