Booker Anke, Jacob Louis, Bohlken Jens, Rapp Michael, Kostev Karel
Int J Clin Pharmacol Ther. 2016 Nov;54(11):835-840. doi: 10.5414/CP202631.
BACKGROUND/AIMS: To analyze the duration of treatment with antipsychotics in German dementia patients.
This study included patients aged 60 years and over with dementia who received a first-time antipsychotic prescription by psychiatrists between 2009 and 2013. The main outcome measure was the treatment rate for more than 6 months following the index date.
A total of 12,979 patients with dementia (mean age 82 years, 52.1% living in nursing homes) were included. After 2 years of follow-up, 54.8%, 57.2%, 61.1%, and 65.4% of patients aged 60 - 69, 70 - 79, 80 - 89, and 90 - 99 years, respectively, received antipsychotic prescriptions. 63.9% of subjects living in nursing homes and 55.0% of subjects living at home also continued their treatment (p-value < 0.001).
CONCLUSION: The percentage of dementia patients treated with antipsychotics is very high. .
背景/目的：分析德国痴呆症患者使用抗精神病药物的治疗时长。
本研究纳入了2009年至2013年间年龄在60岁及以上、患有痴呆症且首次接受精神科医生开具抗精神病药物处方的患者。主要结局指标为索引日期后超过6个月的治疗率。
共纳入12979例痴呆症患者（平均年龄82岁，52.1%居住在养老院）。随访2年后，60 - 69岁、70 - 79岁、80 - 89岁和90 - 99岁的患者中，分别有54.8%、57.2%、61.1%和65.4%接受了抗精神病药物处方。居住在养老院的患者中有63.9%以及居家患者中有55.0%也继续接受治疗（p值<0.001）。
接受抗精神病药物治疗的痴呆症患者比例非常高。
