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肉毒杆菌毒素:一种治疗面神经麻痹所致面部不对称的方法。

Botulinum toxin: a treatment for facial asymmetry caused by facial nerve paralysis.

作者信息

Clark R P, Berris C E

机构信息

Section of Plastic and Reconstructive Surgery, Mercy General Hospital, Sacramento, Calif.

出版信息

Plast Reconstr Surg. 1989 Aug;84(2):353-5.

PMID:2748749
Abstract

Injury to the frontal or other facial nerve branches can result in an asymmetry that can be very distressful to both patient and surgeon. This is especially true following cosmetic procedures such as rhytidectomy. We propose a means to create temporary symmetry while awaiting the possible return of nerve function. Botulinum neurotoxin causes a muscle paralysis lasting for approximately 3 months, and it is well established as the preferred treatment for blepharospasm. A case is presented in which botulinum toxin type A was injected into the opposite functioning frontalis muscle of a patient with unilateral frontal nerve paralysis. The patient experienced satisfactory relief of the asymmetry caused by onesided forehead wrinkling and brow elevation. Botulinum toxin therapy should be considered for both temporary and permanent facial asymmetries due to facial nerve paralysis as well as spasm.

摘要

额神经或其他面神经分支损伤可导致不对称,这对患者和外科医生来说都可能非常苦恼。在诸如除皱术等美容手术后尤其如此。我们提出一种方法,在等待神经功能可能恢复的同时创造暂时的对称。肉毒杆菌神经毒素会导致肌肉麻痹持续约3个月,并且它已被公认为治疗眼睑痉挛的首选方法。本文介绍了一例将A型肉毒杆菌毒素注射到单侧额神经麻痹患者对侧功能正常的额肌中的病例。患者因单侧前额皱纹和眉毛抬高引起的不对称得到了满意的缓解。对于因面神经麻痹以及痉挛导致的暂时和永久性面部不对称,都应考虑肉毒杆菌毒素治疗。

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