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肉毒杆菌毒素注射治疗周围性面神经麻痹后联动有效

[Botulinum toxin injection effective for post-peripheral facial nerve palsy synkinesis].

作者信息

Badarny S, Giladi N, Honigman S

机构信息

Dept. of Neurology, Carmel Medical Center, Haifa.

出版信息

Harefuah. 1998 Aug;135(3-4):106-7, 167.

PMID:9885653
Abstract

Facial synkinesis is an involuntary activation of muscles innervated by the zygomatic or mandibular branch of the facial nerve in conjunction with voluntary activation of the other branch. It appears frequently after recovery from peripheral facial nerve paralysis. We report 10 patients with facial synkinesis following Bell's palsy with a mean duration of synkinesis of 7 +/- 4 years before treatment with periorbital injections of Botulinum toxin type A. 9 had marked subjective and objective improvement starting a few days after injection and lasting 4-9 months. The results suggest a useful treatment option for post-Bell's palsy facial synkinesis with Botulinum toxin type A.

摘要

面部联动是指面神经颧支或下颌缘支支配的肌肉在面神经其他分支的随意运动时出现的不自主激活。它常在周围性面神经麻痹恢复后频繁出现。我们报告了10例贝尔面瘫后出现面部联动的患者,在进行眶周注射A型肉毒杆菌毒素治疗前,面部联动的平均持续时间为7±4年。9例患者在注射后数天开始有明显的主观和客观改善,持续4 - 9个月。结果表明,A型肉毒杆菌毒素是治疗贝尔面瘫后面部联动的一种有效治疗选择。

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1
[Botulinum toxin injection effective for post-peripheral facial nerve palsy synkinesis].肉毒杆菌毒素注射治疗周围性面神经麻痹后联动有效
Harefuah. 1998 Aug;135(3-4):106-7, 167.
2
[Involuntary lid closure caused by defective healing of facial paralysis and its treatment with botulinum toxin].[面神经麻痹愈合不良所致的眼睑闭合不全及其肉毒杆菌毒素治疗]
Klin Monbl Augenheilkd. 1991 Apr;198(4):268-70. doi: 10.1055/s-2008-1045963.
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Therapeutic strategies in post-facial paralysis synkinesis in pediatric patients.小儿面瘫后面神经联带运动的治疗策略。
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Contralateral botulinum injections improve drinking ability and facial symmetry in patients with facial paralysis.对侧肉毒杆菌注射可改善面瘫患者的饮水能力和面部对称性。
Am J Ophthalmol. 2005 Mar;139(3):540. doi: 10.1016/j.ajo.2004.09.035.
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Surgical management of Bell's palsy.贝尔面瘫的外科治疗
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Mirror biofeedback rehabilitation after administration of single-dose botulinum toxin for treatment of facial synkinesis.单次注射肉毒毒素治疗面肌协同运动后进行镜像生物反馈康复。
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Recovery of facial movement and facial synkinesis in Bell's palsy patients.贝尔面瘫患者面部运动及面部联带运动的恢复情况
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Botulinum toxin in the treatment of facial synkinesis and hyperkinesis.肉毒毒素治疗面肌联动和运动过度。
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[Botulinum toxin treatment of synkinesia following facial paralysis].
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引用本文的文献

1
Management of peripheral facial nerve palsy.周围性面神经麻痹的管理
Eur Arch Otorhinolaryngol. 2008 Jul;265(7):743-52. doi: 10.1007/s00405-008-0646-4. Epub 2008 Mar 27.