Loss of MPZL3 function causes seborrhoeic dermatitis-like phenotype in mice.
作者信息
Wikramanayake Tongyu C, Borda Luis J, Kirsner Robert S, Wang Ying, Duffort Stephanie, Reyes-Capo Andres, Barsam Alexander, Urbieta Maite, Perez Victor L
机构信息
Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
出版信息
Exp Dermatol. 2017 Aug;26(8):736-738. doi: 10.1111/exd.13150. Epub 2016 Dec 20.
Abstract
摘要
相似文献
1
Loss of MPZL3 function causes seborrhoeic dermatitis-like phenotype in mice.MPZL3功能丧失导致小鼠出现脂溢性皮炎样表型。
Exp Dermatol. 2017 Aug;26(8):736-738. doi: 10.1111/exd.13150. Epub 2016 Dec 20.
2
Increased IL-17-expressing γδ T cells in seborrhoeic dermatitis-like lesions of the Mpzl3 knockout mice.Mpzl3 基因敲除小鼠皮脂溢性皮炎样皮损中白细胞介素-17 表达的 γδ T 细胞增加。
Exp Dermatol. 2018 Dec;27(12):1408-1411. doi: 10.1111/exd.13798.
3
Seborrheic dermatitis-Looking beyond Malassezia.脂溢性皮炎——超越马拉色菌。
Exp Dermatol. 2019 Sep;28(9):991-1001. doi: 10.1111/exd.14006. Epub 2019 Aug 19.
4
The genetic basis of seborrhoeic dermatitis: a review.脂溢性皮炎的遗传学基础：综述。
J Eur Acad Dermatol Venereol. 2018 Apr;32(4):529-536. doi: 10.1111/jdv.14704. Epub 2017 Dec 15.
5
Loss of Mpzl3 function causes various skin abnormalities and greatly reduced adipose depots.Mpzl3功能丧失会导致各种皮肤异常，并使脂肪储存大幅减少。
J Invest Dermatol. 2014 Jul;134(7):1817-1827. doi: 10.1038/jid.2014.94. Epub 2014 Feb 14.
6
Mutation in Mpzl3, a novel [corrected] gene encoding a predicted [corrected] adhesion protein, in the rough coat (rc) mice with severe skin and hair abnormalities.在具有严重皮肤和毛发异常的粗糙被毛（rc）小鼠中，编码一种预测的黏附蛋白的新基因Mpzl3发生了突变。
J Invest Dermatol. 2007 Jun;127(6):1375-86. doi: 10.1038/sj.jid.5700706. Epub 2007 Feb 1.
7
Inherited seborrheic dermatitis--a new mutant in mice.遗传性脂溢性皮炎——小鼠中的一种新突变体。
Lab Anim. 1987 Oct;21(4):299-305. doi: 10.1258/002367787781363336.
8
Mitochondrially localized MPZL3 emerges as a signaling hub of mammalian physiology.线粒体定位的 MPZL3 成为哺乳动物生理学的信号枢纽。
Bioessays. 2021 Oct;43(10):e2100126. doi: 10.1002/bies.202100126. Epub 2021 Sep 6.
9
Is seborrhoeic dermatitis associated with a diffuse, low-grade folliculitis and progressive cicatricial alopecia?脂溢性皮炎是否与弥漫性、轻度毛囊炎及进行性瘢痕性脱发相关？
Australas J Dermatol. 2016 Aug;57(3):e105-7. doi: 10.1111/ajd.12289. Epub 2015 Mar 5.
10
Inherited disorders of corneocyte proteins.角质形成细胞蛋白的遗传性疾病。
Curr Probl Dermatol. 2010;39:98-131. doi: 10.1159/000321086. Epub 2010 Sep 14.
引用本文的文献
1
Loss of Predicted Cell Adhesion Molecule MPZL3 Promotes EMT in Ovarian Cancer.预测的细胞粘附分子MPZL3缺失促进卵巢癌中的上皮-间质转化。
Cancer Res Commun. 2025 Jul 1;5(7):1180-1193. doi: 10.1158/2767-9764.CRC-24-0591.
2
A narrative review on cutaneous manifestations in polycystic ovary syndrome: pathophysiology, diagnosis, management, and psychosocial impact.多囊卵巢综合征皮肤表现的叙述性综述：病理生理学、诊断、管理及社会心理影响
Ann Med Surg (Lond). 2025 Mar 28;87(5):2804-2811. doi: 10.1097/MS9.0000000000003217. eCollection 2025 May.
3
Development of a biomarker-based platform for comprehensive skin characterization using minimally invasive skin sampling and quantitative real-time PCR.基于生物标志物的平台，使用微创皮肤采样和定量实时 PCR 进行全面皮肤特征分析。
Skin Res Technol. 2024 Aug;30(8):e13908. doi: 10.1111/srt.13908.
4
Alteration in skin mycobiome due to atopic dermatitis and seborrheic dermatitis.特应性皮炎和脂溢性皮炎导致皮肤微生物群的改变。
Biophys Rev (Melville). 2023 Mar 13;4(1):011309. doi: 10.1063/5.0136543. eCollection 2023 Mar.
5
More yeast, more problems?: reevaluating the role of Malassezia in seborrheic dermatitis.更多的酵母，更多的问题？：重新评估马拉色菌在脂溢性皮炎中的作用。
Arch Dermatol Res. 2024 Mar 12;316(4):100. doi: 10.1007/s00403-024-02830-7.
6
Exploration of the common pathogenic link between COVID-19 and diabetic foot ulcers: An in silico approach.2019冠状病毒病与糖尿病足溃疡之间共同致病机制的探索：一种计算机模拟方法。
Health Sci Rep. 2023 Nov 5;6(11):e1686. doi: 10.1002/hsr2.1686. eCollection 2023 Nov.
7
A systemic pan-cancer analysis of MPZL3 as a potential prognostic biomarker and its correlation with immune infiltration and drug sensitivity in breast cancer.MPZL3作为一种潜在的预后生物标志物的全癌系统分析及其与乳腺癌免疫浸润和药物敏感性的相关性
Front Oncol. 2022 Jul 29;12:901728. doi: 10.3389/fonc.2022.901728. eCollection 2022.
8
Met-HER3 crosstalk supports proliferation via MPZL3 in MET-amplified cancer cells.MET-HER3 串扰通过 MET 扩增癌细胞中的 MPZL3 支持增殖。
Cell Mol Life Sci. 2022 Mar 5;79(3):178. doi: 10.1007/s00018-022-04149-w.
9
Minimally invasive skin sampling and transcriptome analysis using microneedles for skin type biomarker research.使用微针进行微创皮肤采样和转录组分析，用于皮肤类型生物标志物研究。
Skin Res Technol. 2022 Mar;28(2):322-335. doi: 10.1111/srt.13135. Epub 2022 Jan 10.
10
Antisense oligonucleotide-mediated knockdown of Mpzl3 attenuates the negative metabolic effects of diet-induced obesity in mice.反义寡核苷酸介导的 Mpzl3 敲低可减轻饮食诱导肥胖小鼠的负面代谢效应。
Physiol Rep. 2021 May;9(9):e14853. doi: 10.14814/phy2.14853.
本文引用的文献
1
Seborrheic Dermatitis and Dandruff: A Comprehensive Review.脂溢性皮炎与头皮屑：综述
J Clin Investig Dermatol. 2015 Dec;3(2). doi: 10.13188/2373-1044.1000019. Epub 2015 Dec 15.
2
Network Analysis Identifies Mitochondrial Regulation of Epidermal Differentiation by MPZL3 and FDXR.网络分析确定了MPZL3和FDXR对表皮分化的线粒体调控。
Dev Cell. 2015 Nov 23;35(4):444-57. doi: 10.1016/j.devcel.2015.10.023.
3
Loss of Mpzl3 function causes various skin abnormalities and greatly reduced adipose depots.Mpzl3功能丧失会导致各种皮肤异常，并使脂肪储存大幅减少。
J Invest Dermatol. 2014 Jul;134(7):1817-1827. doi: 10.1038/jid.2014.94. Epub 2014 Feb 14.
4
Genetic ablation of myelin protein zero-like 3 in mice increases energy expenditure, improves glycemic control, and reduces hepatic lipid synthesis.在小鼠中敲除髓鞘蛋白零样 3 可增加能量消耗、改善血糖控制并减少肝脂质合成。
Am J Physiol Endocrinol Metab. 2013 Jul 15;305(2):E282-92. doi: 10.1152/ajpendo.00228.2013. Epub 2013 May 28.
5
Mutation in Mpzl3, a novel [corrected] gene encoding a predicted [corrected] adhesion protein, in the rough coat (rc) mice with severe skin and hair abnormalities.在具有严重皮肤和毛发异常的粗糙被毛（rc）小鼠中，编码一种预测的黏附蛋白的新基因Mpzl3发生了突变。
J Invest Dermatol. 2007 Jun;127(6):1375-86. doi: 10.1038/sj.jid.5700706. Epub 2007 Feb 1.
6
Seborrhea-like dermatitis with psoriasiform elements caused by a mutation in ZNF750, encoding a putative C2H2 zinc finger protein.由编码假定的C2H2锌指蛋白的ZNF750突变引起的伴有银屑病样成分的脂溢性皮炎样皮炎。
Nat Genet. 2006 Jul;38(7):749-51. doi: 10.1038/ng1813. Epub 2006 Jun 4.
7
A novel T cell receptor transgenic animal model of seborrheic dermatitis-like skin disease.一种新型的脂溢性皮炎样皮肤病的T细胞受体转基因动物模型。
J Invest Dermatol. 2005 Jan;124(1):151-9. doi: 10.1111/j.0022-202X.2004.23565.x.
8
RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement.由于无法启动V(D)J重排，RAG-2缺陷小鼠缺乏成熟淋巴细胞。
Cell. 1992 Mar 6;68(5):855-67. doi: 10.1016/0092-8674(92)90029-c.
Zotero 插件