Pi Jie, Li Xuelin, Zhang Ting, Li Deliang
Collaborative Innovation Center for Efficient and Health Production of Fisheries in Hunan Province, Hunan Engineering Technology Research Center of Featured Aquatic Resources Utilization, College of Animal Science and Technology, Hunan Agricultural University, Changsha, 410128, China.
Center of Environment and Water Resources, College of Chemistry and Chemical Engineering, Central South University, Changsha, 410083, China.
Bull Environ Contam Toxicol. 2016 Oct;97(4):497-503. doi: 10.1007/s00128-016-1896-2. Epub 2016 Aug 3.
Effects of acute exposure to sublethal waterborne cadmium (Cd) on energy homeostasis in filter-feeding fishes have rarely been studied. The response patterns of energy substances were investigated in juvenile silver carp (Hypophthalmichthys molitrix) exposed to sublethal waterborne Cd for 96 h. The results showed the 96hLC50 of Cd on juvenile silver carp was 1.723 mg/L. Sublethal acute exposure of Cd significantly affected the energy homeostasis of juvenile silver carp, including increase in plasma glucose and lactate, and decrease in plasma triglyceride, muscle glycogen and triglyceride and liver glycogen. The results indicated that glycogen and triglyceride prior to protein were mobilized to meet the increased demands for detoxication and repair mechanism to sublethal waterborne Cd exposure, and glycogen level depleted faster and restored slower in the liver than in the white muscle in juvenile silver carp.
急性暴露于亚致死剂量的水体镉（Cd）对滤食性鱼类能量平衡的影响鲜有研究。本研究调查了暴露于亚致死剂量水体Cd 96小时的幼鱼白鲢（Hypophthalmichthys molitrix）体内能量物质的响应模式。结果显示，Cd对幼鱼白鲢的96hLC50为1.723 mg/L。亚致死剂量的急性Cd暴露显著影响了幼鱼白鲢的能量平衡，包括血浆葡萄糖和乳酸增加，以及血浆甘油三酯、肌肉糖原和甘油三酯及肝糖原减少。结果表明，在幼鱼白鲢中，相较于蛋白质，糖原和甘油三酯先被调动以满足对亚致死剂量水体Cd暴露的解毒和修复机制增加的需求，且肝脏中糖原水平的消耗速度比白色肌肉更快，恢复速度更慢。
