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一名印度女性出现奥硝唑诱发的共济失调:病例报告。

Ornidazole-induced ataxia in an Indian woman: A case report.

作者信息

Gopinath Kango Gopal, Wilson Benny Paul, Viggeswarpu Surekha, Mathews Prasad K, Mani Sunithi

机构信息

Department of Geriatric Medicine, Christian Medical College (CMC), Vellore, India.

Department of Radiology, Christian Medical College (CMC), Vellore, India.

出版信息

SAGE Open Med Case Rep. 2015 Dec 15;3:2050313X15621857. doi: 10.1177/2050313X15621857. eCollection 2015.

Abstract

The nitroimidazole group of antibiotics like metronidazole have been reported to cause cerebellar ataxia as a rare side effect. Ornidazole, the newest derivative of this class, has a long half life and is very rarely known to cause cerebellar ataxia. Here, we report a 61-year-old patient who developed ataxia due to ornidazole to highlight an unusual adverse event that improved rapidly after discontinuation of the offending drug.

摘要

据报道,像甲硝唑这类抗生素的硝基咪唑基团会引起小脑共济失调,这是一种罕见的副作用。奥硝唑是此类药物的最新衍生物,半衰期长,极少会引起小脑共济失调。在此,我们报告一名61岁因奥硝唑导致共济失调的患者,以突出这一不寻常的不良事件,该事件在停用致病药物后迅速好转。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a2e9/4857303/bf581dd3caaa/10.1177_2050313X15621857-fig1.jpg

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