实体器官移植患者的疫苗接种策略：证据与未来展望。
Vaccination strategies in patients with solid organ transplant: evidences and future perspectives.
作者信息
Kim Youn Jeong, Kim Sang Il
机构信息
Division of Infectious Disease, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
出版信息
Clin Exp Vaccine Res. 2016 Jul;5(2):125-31. doi: 10.7774/cevr.2016.5.2.125. Epub 2016 Jul 29.
Abstract
Solid organ transplant recipients need emphases on immunization that result in certainly decrease the risk of vaccine preventable diseases. Organ transplant candidate should complete the recommended full vaccination schedule as early as possible during the courses of underlying disease because the patients with end stage liver or renal disease have reduced immune response to vaccine. Furthermore, live attenuated vaccines are generally contraindicated after transplantation. This review summarizes current information and the evidences regarding the efficacy and safety of immunization in adult solid organ transplant candidates and recipients.
摘要
实体器官移植受者需要重视免疫接种，这肯定会降低疫苗可预防疾病的风险。器官移植候选人应在基础疾病病程中尽早完成推荐的全程疫苗接种计划，因为终末期肝病或肾病患者对疫苗的免疫反应会降低。此外，减毒活疫苗在移植后通常是禁忌的。本综述总结了有关成人实体器官移植候选者和受者免疫接种的有效性和安全性的当前信息及证据。
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