因富克斯内皮营养不良行准分子原位角膜磨镶术（LASIK）后出现的界面液综合征经后弹力层内皮角膜移植术（DMEK）逆转。
Interface Fluid Syndrome After Laser In Situ Keratomileusis (LASIK) Because of Fuchs Endothelial Dystrophy Reversed by Descemet Membrane Endothelial Keratoplasty (DMEK).
作者信息
Luceri Salvatore, Baksoellah Zainab, Ilyas Abbas, Baydoun Lamis, Melles Gerrit R J
机构信息
*Netherlands Institute for Innovative Ocular Surgery, Rotterdam, the Netherlands; and†Melles Cornea Clinic Rotterdam, Rotterdam, the Netherlands.
出版信息
Cornea. 2016 Dec;35(12):1658-1661. doi: 10.1097/ICO.0000000000000971.
PURPOSE
To describe a case that developed "interface fluid syndrome" after previous laser in situ keratomileusis (LASIK) because of Fuchs endothelial dystrophy (FED), which was reversed by Descemet membrane endothelial keratoplasty (DMEK).
METHODS
A 58-year-old male patient presented with bilateral visual impairment owing to FED and visually significant cataract. Cataract surgery was carried out in both eyes followed by DMEK in his left eye.
RESULTS
After cataract surgery, visual acuity did not improve sufficiently because corneal thickness increased and a fine cleft with interface fluid developed between the LASIK-flap and the residual stromal bed. After uneventful DMEK in his left eye, the fluid resolved within a week and visual acuity improved rapidly.
CONCLUSIONS
This case demonstrates that "interface fluid syndrome" after LASIK caused by concomitant endothelial dysfunction may be reversed by DMEK allowing fast visual recovery.
目的
描述一例因富克斯内皮营养不良（FED）在先前准分子原位角膜磨镶术（LASIK）后发生“界面液综合征”的病例，该综合征通过Descemet膜内皮角膜移植术（DMEK）得以逆转。
方法
一名58岁男性患者因FED和具有明显视觉影响的白内障导致双眼视力受损。双眼均进行了白内障手术，随后左眼进行了DMEK。
结果
白内障手术后，视力改善不充分，因为角膜厚度增加，且在LASIK瓣和残余基质床之间出现了伴有界面液的细微裂隙。左眼DMEK术后恢复顺利，一周内液体消退，视力迅速提高。
结论
该病例表明，由合并的内皮功能障碍引起的LASIK术后“界面液综合征”可通过DMEK逆转，实现快速视力恢复。
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