液体管理：药物治疗和肾脏替代疗法
Fluid Management: Pharmacologic and Renal Replacement Therapies.
作者信息
Wald Eric L, Finer Gal, McBride Mary E, Nguyen Nguyenvu, Costello John M, Epting Conrad L
机构信息
1Divisions of Critical Care and Cardiology, Department of Pediatrics, Northwestern University Feinberg School of Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL. 2Division of Kidney Diseases, Department of Pediatrics, Northwestern University Feinberg School of Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL. 3Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL.
出版信息
Pediatr Crit Care Med. 2016 Aug;17(8 Suppl 1):S257-65. doi: 10.1097/PCC.0000000000000781.
OBJECTIVES
Focusing on critically ill children with cardiac disease, we will review common causes of fluid perturbations, clinical recognition, and strategies to minimize and treat fluid-related complications.
DATA SOURCE
MEDLINE and PubMed.
CONCLUSIONS
Meticulous fluid management is vital in critically ill children with cardiac disease. Fluid therapy is important to maintain adequate blood volume and perfusion pressure in order to support cardiac output, tissue perfusion, and oxygen delivery. However, fluid overload and acute kidney injury are common and are associated with increased morbidity and mortality. Understanding the etiologies for disturbances in volume status and the pathophysiology surrounding those conditions is crucial for providing optimal care.
目的
聚焦患有心脏病的危重症儿童，我们将回顾液体紊乱的常见原因、临床识别方法以及将与液体相关的并发症降至最低并进行治疗的策略。
数据来源
医学在线数据库（MEDLINE）和医学期刊数据库（PubMed）。
结论
精心的液体管理对患有心脏病的危重症儿童至关重要。液体疗法对于维持充足的血容量和灌注压以支持心输出量、组织灌注和氧气输送非常重要。然而，液体超负荷和急性肾损伤很常见，且与发病率和死亡率的增加相关。了解容量状态紊乱的病因以及围绕这些情况的病理生理学对于提供最佳护理至关重要。
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