Hu Zhiqiang, Kang Zhuang, Zhu Guangtong, Tu Jian, Huang Hui, Guan Feng, Dai Bin, Mao Beibei
Department of Neurosurgery, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
Department of Neuroscience, The Prince of Wales Hospital, University of New South Wales, Sydney, Australia.
J Neurol Surg A Cent Eur Neurosurg. 2017 Mar;78(2):132-136. doi: 10.1055/s-0035-1564050. Epub 2016 Aug 4.
The increase in intracranial pressure (ICP) in some patients in the immediate postoperative period following endoscopic third ventriculostomy (ETV) is not well understood. This study explored the effect of lumbar puncture following ETV for obstructive hydrocephalus on outcome. A total of 145 patients with obstructive hydrocephalus underwent ETV between 2009 and 2014. Following ETV, all patients underwent lumbar puncture on postoperative days 1 and 3. In 106 patients, ICP returned to normal levels accompanied by symptom relief. In 39 patients, ICP remained high on postoperative days 3, and lumbar puncture was continued every alternate postoperative day for 11 days. ICP always returned to normal. These 39 patients were divided into two groups for analysis: group A (age < 18 years) and group B (age ≥ 18 years). Peak values of ICP for groups A and B were recorded on days 3 and 5, respectively. Our study suggests an important role for postoperative lumbar puncture in ensuring successful treatment results after ETV. In most of the symptomatic patients with obstructive hydrocephalus, lumbar puncture appears to contribute to rapid ICP normalization, to alleviation of symptoms, and prevention of complications.
内镜下第三脑室造瘘术(ETV)后部分患者在术后即刻出现颅内压(ICP)升高的原因尚不清楚。本研究探讨了ETV治疗梗阻性脑积水后行腰椎穿刺对预后的影响。2009年至2014年间,共有145例梗阻性脑积水患者接受了ETV治疗。ETV术后,所有患者在术后第1天和第3天进行腰椎穿刺。106例患者的ICP恢复至正常水平,症状缓解。39例患者在术后第3天ICP仍较高,术后每隔一天继续进行腰椎穿刺,持续11天。ICP最终均恢复正常。这39例患者分为两组进行分析:A组(年龄<18岁)和B组(年龄≥18岁)。A组和B组的ICP峰值分别在第3天和第5天记录。我们的研究表明,术后腰椎穿刺对确保ETV治疗成功具有重要作用。在大多数有症状的梗阻性脑积水患者中,腰椎穿刺似乎有助于ICP迅速恢复正常、缓解症状并预防并发症。