Yamamoto N, Kurotani T, Toyama K
Department of Physiology, Kyoto Prefectural School of Medicine, Japan.
Science. 1989 Jul 14;245(4914):192-4. doi: 10.1126/science.2749258.
Neural connections were established in cocultures of rat visual cortex (VC) and lateral geniculate nucleus (LGN), which were isolated in early infancy. Morphological and electrophysiological studies showed that the cortical laminar organization of afferent and efferent connections in the coculture preparations was similar to that in the adult VC. The results indicate the existence of intrinsic mechanisms in VC and LGN that guide the formation of synaptic connections with the appropriate targets.
在幼年早期分离的大鼠视觉皮层（VC）和外侧膝状体核（LGN）的共培养物中建立了神经连接。形态学和电生理学研究表明，共培养制剂中传入和传出连接的皮质层状组织与成年VC中的相似。结果表明，VC和LGN中存在内在机制，可指导与适当靶标的突触连接形成。
