Zhang Min, Zhang Xuhui, Zhang Bin, Wang Dongwen
Department of Urology, First Hospital of Shanxi Medical University, Taiyuan, China.
First Clinical Medical College, Shanxi Medical University, Taiyuan, China.
Microsc Res Tech. 2016 Nov;79(11):1038-1044. doi: 10.1002/jemt.22739. Epub 2016 Aug 5.
To better understand the basis of urinary calculi formation, we studied the composition, microstructure, and element analysis of different types of urinary calculi. Sixty people with urinary stones in Shanxi province were selected randomly. The composition of urinary stones was analyzed using Fourier transform infrared spectroscopy. The microstructure of material components was observed by a scanning electron microscopy and the elemental distribution and composition were analyzed by an X-ray energy spectrometer. Furthermore, general information, BMI, history of medicine, chronic medical history, family history, and recurrence rates were collected. Female-to-male ratio was 1:2.5; median age was 43.2 years old. Of the patients, 13.3% were found definite family history and 46.6% of patients for recurrence history. It was found that mixed stones account for the largest proportion (65%), followed by calcium oxalate monohydrate calculi (26.67%). In mixed stones, the mixture of calcium oxalate monohydrate and hydroxyapatite had the largest proportion, accounting for 71.79%. Stones showed different microcosmic characteristics and element distribution. Stones varied widely in distribution, infrared spectrum, microstructure, and element composition, which provided an important basis for urinary calculi research regarding urinary stone formation.
为了更好地理解尿结石形成的基础，我们研究了不同类型尿结石的成分、微观结构和元素分析。随机选取了山西省60例尿结石患者。采用傅里叶变换红外光谱法分析尿结石的成分。通过扫描电子显微镜观察材料成分的微观结构，并用X射线能谱仪分析元素分布和组成。此外，收集了患者的一般信息、体重指数、用药史、慢性病史、家族史和复发率。男女比例为1:2.5；中位年龄为43.2岁。在患者中，发现13.3%有明确家族史，46.6%有复发史。结果发现，混合结石占比最大（65%），其次是一水草酸钙结石（26.67%）。在混合结石中，一水草酸钙与羟基磷灰石的混合物占比最大，为71.79%。结石表现出不同的微观特征和元素分布。结石在分布、红外光谱、微观结构和元素组成方面差异很大，这为尿结石形成的尿结石研究提供了重要依据。
