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阿尔茨海默病患者在视觉空间和言语工作记忆广度任务中的抑制效应:一项为期2年的随访研究。

The suppression effect in visuospatial and verbal working memory span tasks in patients with Alzheimer's disease: a 2-year follow-up study.

作者信息

Elosúa M Rosa, Peinado Matías, Contreras María José, Reales J Manuel, Montoro Pedro R

机构信息

a Departamento Psicología Básica I, Facultad de Psicología , Universidad Nacional de Educación a Distancia (UNED) , Madrid , Spain.

b France Alzheimer-Var Association and Alzheimer-Aidants 83 , Toulon , France.

出版信息

Neurocase. 2016 Oct;22(5):426-435. doi: 10.1080/13554794.2016.1216571. Epub 2016 Aug 5.

Abstract

This study adapted a new task to assess visuospatial and verbal working memory impairments in patients with Alzheimer Disease (AD), including an executive strategy of information suppression. The aim was to examine the visuospatial and verbal difficulties, and additionally to explore the average sex differences, during a 2-year follow-up study. The results indicated that patients with AD showed a significantly lower performance, compared with healthy elderly controls, especially with the suppression of information required in this new task. However, suppression did not lead to a significantly greater decline in the performance of patients when compared with the control group.

摘要

本研究采用了一项新任务来评估阿尔茨海默病(AD)患者的视觉空间和言语工作记忆损伤,其中包括信息抑制的执行策略。目的是在一项为期2年的随访研究中,检查视觉空间和言语方面的困难,并进一步探索平均性别差异。结果表明,与健康老年对照组相比,AD患者的表现显著较低,尤其是在抑制这项新任务所需信息方面。然而,与对照组相比,抑制并没有导致患者表现出现显著更大程度的下降。

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