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The suppression effect in visuospatial and verbal working memory span tasks in patients with Alzheimer's disease: a 2-year follow-up study.阿尔茨海默病患者在视觉空间和言语工作记忆广度任务中的抑制效应：一项为期2年的随访研究。
Neurocase. 2016 Oct;22(5):426-435. doi: 10.1080/13554794.2016.1216571. Epub 2016 Aug 5.
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Sex differences in cognitive impairment in Alzheimer's disease.阿尔茨海默病认知障碍的性别差异。
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Visual memory profiling with CANTAB in mild cognitive impairment (MCI) subtypes.使用剑桥神经心理测试自动化成套系统（CANTAB）对轻度认知障碍（MCI）亚型进行视觉记忆剖析
Int J Geriatr Psychiatry. 2014 Oct;29(10):1040-8. doi: 10.1002/gps.4095. Epub 2014 Mar 14.
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The neuropsychological profile of Alzheimer disease.阿尔茨海默病的神经心理学特征。
Cold Spring Harb Perspect Med. 2012 Apr;2(4):a006171. doi: 10.1101/cshperspect.a006171.
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Working memory: theories, models, and controversies.工作记忆：理论、模型与争议
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The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease.阿尔茨海默病所致痴呆的诊断：美国国家老龄化研究所-阿尔茨海默病协会工作组关于阿尔茨海默病诊断指南的建议。
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The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease.阿尔茨海默病所致轻度认知障碍的诊断：美国国家老龄化研究所-阿尔茨海默病协会诊断指南工作组的建议。
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轻度认知障碍和阿尔茨海默病患者在言语和视觉空间工作记忆任务中的性别差异

Gender Differences in Verbal and Visuospatial Working Memory Tasks in Patients with Mild Cognitive Impairment and Alzheimer Disease.

作者信息

Elosúa M Rosa, Ciudad María José, Contreras María José

机构信息

Universidad Nacional de Educación a Distancia (UNED), Madrid, Spain.

Geriatrics and Palliative Care, Badalona Serveis Assistencials, Badalona, Spain.

出版信息

Dement Geriatr Cogn Dis Extra. 2017 Apr 3;7(1):101-108. doi: 10.1159/000466689. eCollection 2017 Jan-Apr.

DOI:10.1159/000466689
PMID:28553312
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5425757/
Abstract

BACKGROUND/AIMS: To date, there are few studies on gender differences in patients with mild cognitive impairment (MCI) and Alzheimer disease (AD). In the present study, the existence of differences between sexes in verbal and visuospatial working memory tasks in the evolution of cognitive and pathological aging was examined.

METHOD

Ninety participants took part in this study: 30 AD, 30 MCI, and 30 healthy elderly participants (50% men and 50% women).

RESULTS

There were no significant differences between men and women with AD in visuospatial tasks, whereas these differences were found within the MCI group, with the average of men achieving significantly higher results than women. In verbal tasks, there were no differences between sexes for any of the groups.

CONCLUSION

Execution in visuospatial tasks tends to depend on gender, whereas this does not occur for verbal tasks.

摘要

背景/目的：迄今为止，关于轻度认知障碍（MCI）和阿尔茨海默病（AD）患者性别差异的研究较少。在本研究中，我们检验了在认知和病理性衰老过程中，言语和视觉空间工作记忆任务中性别差异的存在情况。

方法

90名参与者参与了本研究：30名AD患者、30名MCI患者和30名健康老年参与者（男性和女性各占50%）。

结果

AD患者在视觉空间任务上男女之间无显著差异，而在MCI组中发现了这些差异，男性的平均成绩显著高于女性。在言语任务中，任何一组的男女之间均无差异。

结论

视觉空间任务的执行往往取决于性别，而言语任务则不然。