Adeel Ahmed Awad
Department of Microbiology and Pathology, King Khalid University Hospital and College of Medicine, King Saud University , Riyadh , Saudi Arabia.
Sudan J Paediatr. 2015;15(2):80-99.
John Brian Christopherson (1868-1955) was one of the first doctors to be recruited to serve in the Sudan under the British colonial rule. During his work in Sudan (1902-1919) he was key in establishing the civilian medical services in Sudan, including establishing Khartoum Civil Hospital (opened in 1909). The present article focuses on the work of Dr Christopherson in Khartoum Civil Hospital in which he introduced tartar emetic for the first time for the treatment of schistosomiasis. To validate this treatment, Christopherson conducted a series of clinical trials and published his findings in leading medical journals. He had to respond to priority claims over this discovery and to deal with skepticism about the safety of this new treatment. The publications of Christopherson covered not only the therapeutic efficacy of the drug but also discussed the epidemiology of the disease, the possible role of mass chemotherapy and also envisioned chemotherapy in school-age children as a possible strategy for future elimination of the disease.
约翰·布莱恩·克里斯托弗森（1868 - 1955）是首批受雇于英国殖民统治下苏丹地区的医生之一。在他于苏丹工作期间（1902 - 1919），他在苏丹建立平民医疗服务体系方面发挥了关键作用，包括建立喀土穆市民医院（于1909年开业）。本文聚焦于克里斯托弗森医生在喀土穆市民医院的工作，他在那里首次引入吐酒石用于治疗血吸虫病。为了验证这种治疗方法，克里斯托弗森进行了一系列临床试验，并在主流医学期刊上发表了他的研究结果。他不得不回应关于这一发现的优先权主张，并应对对这种新疗法安全性的质疑。克里斯托弗森的出版物不仅涵盖了该药物的治疗效果，还讨论了该疾病的流行病学、大规模化疗的可能作用，并设想将学龄儿童化疗作为未来消除该疾病的一种可能策略。
