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波兰肝脏移植登记处:死者和活体供体肝脏移植的网络质量工具

Liver Transplant Registry in Poland: Web-Netted Quality Tool in Liver Transplantation From Deceased and Living Donors.

作者信息

Czerwiński J, Lewandowska D, Małkowski P, Danielewicz R

机构信息

Polish Transplant Coordinating Center Poltransplant, Warsaw, Poland; Department of Surgical and Transplant Nursing, Medical University of Warsaw, Warsaw, Poland.

Polish Transplant Coordinating Center Poltransplant, Warsaw, Poland; Department of Transplantation Medicine and Nephrology, Medical University of Warsaw, Poland.

出版信息

Transplant Proc. 2016 Jun;48(5):1347-9. doi: 10.1016/j.transproceed.2016.01.059.

DOI:10.1016/j.transproceed.2016.01.059
PMID:27496402
Abstract

BACKGROUND

Poltransplant managed a national transplant registry with the use of the Web tool www.rejestry.net. It collects information about all organ transplantations in the country along with outcomes. This article presents a formal analysis of data collected in the registry for the years 1998 to 2014.

MATERIALS AND METHODS

Results presented are actual, not extrapolated, numbers; these were calculated only for the events for which the observation was complete, meaning that a given term of follow-up had passed and the information on recipient's and graft survivals were available.

RESULTS

All liver transplant procedures were registered from the years 1998 to 2014, with follow-up data completeness of 89% to 99%. Detailed statistical descriptions of liver transplant results were significantly better for transplants from living donors, in comparison to deceased donors, for pediatric recipients. Results for pediatric and adult recipients did not vary if the organ was from a deceased donor. Elective and primary transplantations have significantly better results in comparison to urgent and re-transplanted cases. Results depend on indications for transplantation. Significantly better results were obtained in the case of cholestatic diseases and cirrhosis other than hepatitis C virus. Significantly worse results were obtained in acute liver failure, independently of etiology. Results in the case of hepatitis C virus cirrhosis, metabolic diseases, and neoplasms do not vary significantly.

CONCLUSIONS

The strength of these findings are based on the registry's reliability and completeness. The registry fulfills its aims related to collecting records and monitoring graft function, and recipient survival. The data are an important source of information, to be used by transplantation institutions and referred to in the literature.

摘要

背景

Poltransplant通过网络工具www.rejestry.net管理一个全国性的移植登记处。它收集该国所有器官移植的信息以及相关结果。本文对1998年至2014年登记处收集的数据进行了正式分析。

材料与方法

所呈现的结果是实际数字,而非推断数字;这些数字仅针对观察完整的事件进行计算,即已过给定随访期且可获取受者和移植物存活信息。

结果

1998年至2014年期间记录了所有肝移植手术,随访数据完整性为89%至99%。与已故供体肝移植相比,活体供体肝移植的详细统计描述在儿科受者中明显更好。对于来自已故供体的器官,儿科和成人受者的结果没有差异。择期和初次移植的结果明显优于紧急和再次移植的病例。结果取决于移植指征。胆汁淤积性疾病和丙型肝炎病毒以外的肝硬化患者的结果明显更好。急性肝衰竭患者的结果明显更差,与病因无关。丙型肝炎病毒肝硬化、代谢性疾病和肿瘤患者的结果没有显著差异。

结论

这些发现的优势基于登记处的可靠性和完整性。该登记处实现了其与收集记录、监测移植物功能和受者存活相关的目标。这些数据是移植机构使用并在文献中引用的重要信息来源。

相似文献

1
Liver Transplant Registry in Poland: Web-Netted Quality Tool in Liver Transplantation From Deceased and Living Donors.波兰肝脏移植登记处:死者和活体供体肝脏移植的网络质量工具
Transplant Proc. 2016 Jun;48(5):1347-9. doi: 10.1016/j.transproceed.2016.01.059.
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Liver Donation and Transplantation in Poland: Numbers, Indicators, and Trends.波兰的肝脏捐赠与移植:数量、指标及趋势
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