Nowak E, Pfitzner R, Przybyłowski P
Brothers Hospitallers' of St. John of God Hospital, Department of Angiology, Internal and Geriatric Medicine, Kraków, Poland.
Jagiellonian University, Department of Cardiovascular Surgery and Transplantology, John Paul II Hospital, Kraków, Poland.
Transplant Proc. 2016 Jun;48(5):1394-8. doi: 10.1016/j.transproceed.2016.01.040.
The Polish definition of brain death originated from the original Harvard criteria and has been revised several times. Practitioners worldwide are required to regularly update their national guidelines on the definition of brain death to fit the latest international research concerning this topic.
(1) Compare current Polish guidelines on diagnosing brain death in adults with the American, British, Australian, and New Zealand recommendations; and (2) evaluate existing differences for the purposes of updating the Polish guidelines.
Current guidelines on diagnosing brain death published by The American Academy of Neurology (USA, 2010), the Academy of Medical Royal Colleges (United Kingdom, 2008), the Australian and New Zealand Intensive Care Society (AU/NZ, 2013), and the Polish Ministry of Health (Poland, 2007).
All guidelines outline similar recommendations regarding the need for a suitable observation period before clinical examination and for basic medical conditions and exclusions to be evaluated before testing, the obligatory role of clinical examination including brain stem reflexes and apnea testing, and the nonobligatory role of ancillary tests. There is no consensus regarding: the recommended time period of pretesting observation, the number, seniority, and specialty of clinicians performing the testing, the role of additional exclusion criteria, the repeatability of clinical tests, the methodology of apnea testing, and recommended confirmatory tests.
Current Polish guidelines on diagnosing brain death in adults remain up-to-date in comparison to the guidelines analyzed, though additional recommendations concerning apnea testing, drug and toxin clearance, and medical exclusion criteria for potential brain dead patients might be considered an important point of interest in the future.
波兰脑死亡的定义源自最初的哈佛标准,并经过多次修订。全球从业者需要定期更新其国家关于脑死亡定义的指南,以适应有关该主题的最新国际研究。
(1)将波兰当前关于成人脑死亡诊断的指南与美国、英国、澳大利亚和新西兰的建议进行比较;(2)评估现有差异,以便更新波兰的指南。
美国神经病学学会(美国,2010年)、皇家医学院学会(英国,2008年)、澳大利亚和新西兰重症监护学会(澳大利亚/新西兰,2013年)以及波兰卫生部(波兰,2007年)发布的当前关于脑死亡诊断的指南。
所有指南都概述了类似的建议,包括在临床检查前需要有适当的观察期,在测试前要评估基本医疗状况和排除因素,临床检查(包括脑干反射和呼吸暂停测试)的强制性作用,以及辅助测试的非强制性作用。在以下方面没有达成共识:测试前观察的推荐时间段、进行测试的临床医生的数量、资历和专业、额外排除标准的作用、临床测试的可重复性、呼吸暂停测试的方法以及推荐的确认性测试。
与所分析的指南相比,波兰当前关于成人脑死亡诊断的指南仍然是最新的,不过关于呼吸暂停测试、药物和毒素清除以及潜在脑死亡患者的医学排除标准的额外建议,可能会在未来被视为一个重要的关注点。