匹莫范色林治疗帕金森病精神病的作用机制：靶向5-羟色胺5HT2A和5HT2C受体
Mechanism of action of pimavanserin in Parkinson's disease psychosis: targeting serotonin 5HT2A and 5HT2C receptors.
作者信息
Stahl Stephen M
出版信息
CNS Spectr. 2016 Aug;21(4):271-5. doi: 10.1017/S1092852916000407.
PMID:27503570
Abstract
Pimavanserin, a novel agent approved for the treatment of Parkinson's disease psychosis, has potent actions as an antagonist/inverse agonist at serotonin 5HT2A receptors and less potent antagonist/inverse agonist actions at 5HT2C receptors.
摘要
匹莫范色林是一种被批准用于治疗帕金森病精神病的新型药物，它作为5-羟色胺5HT2A受体的拮抗剂/反向激动剂具有强效作用，而作为5HT2C受体的拮抗剂/反向激动剂作用则较弱。
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