Krasnov V I, Kokhanenko E M
Zh Nevropatol Psikhiatr Im S S Korsakova. 1989;89(4):101-5.
Cortisol and hypophyseal hormones contents were measured in the blood serum of circular, schizophrenic and psychogenic depressed patients during pharmacotherapy. Distinct nosological differences in hypophyseal hormone secretion were noted. The increase in blood serum levels of ACTH, prolactin and somatotropic hormones were obligatory stages of the positive therapeutic effect in circular depressions. The ACTH and prolactin decrease was characteristic of schizophrenic depression. The cortisol level decreased in any depression with positive therapeutic effect.
在药物治疗期间,对循环型、精神分裂症型和心因性抑郁症患者的血清中的皮质醇和垂体激素含量进行了测量。发现垂体激素分泌存在明显的疾病分类差异。促肾上腺皮质激素(ACTH)、催乳素和生长激素血清水平的升高是循环型抑郁症积极治疗效果的必经阶段。ACTH和催乳素降低是精神分裂症型抑郁症的特征。在任何具有积极治疗效果的抑郁症中,皮质醇水平都会降低。