miR379 - 410簇的微小RNA：胚胎神经发生中的新角色及神经元功能的调节因子。
MicroRNAs of the miR379-410 cluster: New players in embryonic neurogenesis and regulators of neuronal function.
作者信息
Winter Jennifer
机构信息
Institute of Human Genetics; University Medical Centre Mainz ; Mainz, Germany.
出版信息
Neurogenesis (Austin). 2015 Mar 4;2(1):e1004970. doi: 10.1080/23262133.2015.1004970. eCollection 2015.
Abstract
The imprinted miR379-410 cluster contains 38 microRNAs (miRNAs) that are involved in diverse neurodevelopmental processes and are important regulators of neuronal function. The implications of these miRNAs in neurological diseases have been recently recognized.In the present minireview, the current findings regarding the brain-specific functions of miR379-410 cluster miRNAs are summarized and discussed.
摘要
印记miR379 - 410簇包含38个微小RNA（miRNA），它们参与多种神经发育过程，是神经元功能的重要调节因子。这些miRNA在神经疾病中的意义最近已得到认可。在本综述中，总结并讨论了关于miR379 - 410簇miRNA脑特异性功能的当前研究结果。
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