Iwasaki Takanori, Akimoto Ryo, Kuniyasu Hitoshi, Kambe Nobuaki
Department of Applied Chemistry Graduate School of Engineering, Osaka University, Suita, Osaka, 565-0871, Japan.
Chem Asian J. 2016 Oct 20;11(20):2834-2837. doi: 10.1002/asia.201600972. Epub 2016 Sep 13.
Iron-catalyzed cross-coupling reaction of vinylic ethers with aryl Grignard reagents is described. The reaction proceeded at room temperature with catalytic amounts of an iron salt without the aid of costly ligands and additives. In this catalytic system, vinylic C-O bonds were preferentially cleaved over aromatic C-O bonds of aryl ethers or aryl sulfonates.
描述了铁催化的乙烯基醚与芳基格氏试剂的交叉偶联反应。该反应在室温下，使用催化量的铁盐即可进行，无需昂贵的配体和添加剂。在这个催化体系中，乙烯基的C-O键比芳基醚或芳基磺酸盐的芳族C-O键更优先被裂解。
