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[关于监狱人群中潜伏性结核感染患病率和发病率的系统评价]

[A SYSTEMATIC REVIEW ON THE PREVALENCE AND INCIDENCE OF LATENT TUBERCULOSIS INFECTION AMONG PRISON POPULATION].

作者信息

Kawatsu Lisa, Uchimura Kazuhiro, Izumi Kiyohiko, Ohkado Akihiro

出版信息

Kekkaku. 2016 Apr;91(4):457-64.

Abstract

SETTING

We conducted a systematic review of literatures on the prevalence and incidence of latent tuberculosis infection in correctional settings, with the aim of offering one of the resources to guide establishment of policies on screening for and treating LTBI among prisoners in Japan.

OBJECTIVE

Using the keywords "latent tuberculosis AND (prison OR jail OR correctional)" and "tuberculosis infection AND (prison OR jail OR correctional)", we conducted a systematic review of relevant literatures on PubMed and secondary searches from the reference list of primary sources. We limited our search to those original articles published since 1980, and in English.

RESULTS

55 articles were identified, and 15 were subject to the systematic review. Of the 12 articles on prevalence of LTBI, 5 were from middle and high-burden and 7 from low-burden countries. The average prevalence of LTBI among middle and high-burden countries was 73.0%, and among low-burden countries, 40.3%. "Duration of incarceration" and "history of previous incarceration" were identified as risk factors for high LTBI prevalence which were specific to the prison population. Incidence of LTBI among the high-burden country was 61.8 per 100 person years, while 5.9 and 6.3 in the two reports from low-burden countries.

CONCLUSION

Prevalence and incidence of LTBI were higher than the general population, both in middle/high- and low-burden countries. The fact that "duration of incarceration" and "history of previous incarceration" were identified as risk factors indicate that high prevalence of LTBI among prison population is not just attributable to the characteristics of prisoners themselves, but also to the possibility of TB infection occurring in prison settings.

摘要

背景

我们对惩教机构中潜伏性结核感染的患病率和发病率的文献进行了系统综述,旨在提供一种资源,以指导日本制定囚犯潜伏性结核感染筛查和治疗政策。

目的

使用关键词“潜伏性结核与(监狱或看守所或惩教机构)”以及“结核感染与(监狱或看守所或惩教机构)”,我们在PubMed上对相关文献进行了系统综述,并从主要来源的参考文献列表中进行了二次检索。我们将搜索范围限制在1980年以来发表的英文原创文章。

结果

共识别出55篇文章,其中15篇纳入系统综述。在12篇关于潜伏性结核感染患病率的文章中,5篇来自高负担和中等负担国家,7篇来自低负担国家。高负担和中等负担国家潜伏性结核感染的平均患病率为73.0%,低负担国家为40.3%。“监禁时间”和“既往监禁史”被确定为监狱人群中潜伏性结核感染患病率高的特定危险因素。高负担国家潜伏性结核感染的发病率为每100人年61.8例,而低负担国家的两份报告中分别为5.9例和6.3例。

结论

在高负担和中等负担国家以及低负担国家,潜伏性结核感染的患病率和发病率均高于普通人群。“监禁时间”和“既往监禁史”被确定为危险因素这一事实表明,监狱人群中潜伏性结核感染的高患病率不仅归因于囚犯自身的特征,还归因于监狱环境中发生结核感染的可能性。

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