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婴儿下颌骨牵引治疗上气道梗阻:一项临床审计

Infant Mandibular Distraction for Upper Airway Obstruction: A Clinical Audit.

作者信息

Adhikari Ashim N, Heggie Andrew A C, Shand Jocelyn M, Bordbar Patrishia, Pellicano Anastasia, Kilpatrick Nicky

机构信息

Faculty of Medicine, Dentistry and Health Sciences and Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia; Head, Oral & Maxillofacial Surgery Unit, Department of Plastic and Maxillofacial Surgery, the Royal Children's Hospital, Melbourne, Victoria, Australia; Department of Neonatology, Royal Children's Hospital, Melbourne, Victoria, Australia; and Plastic Surgery Research, Murdoch Childrens Research Institute, the Royal Children's Hospital, Melbourne, Victoria, Australia.

出版信息

Plast Reconstr Surg Glob Open. 2016 Jul 20;4(7):e812. doi: 10.1097/GOX.0000000000000822. eCollection 2016 Jul.

Abstract

BACKGROUND

Mandibular distraction osteogenesis (MDO) is an effective method of treating upper airway obstruction (UAO) in micrognathic infants. The short-term outcomes include relief of UAO, avoidance of tracheostomy, and prompt discharge from hospital. However, it is a significant surgical procedure with potential associated morbidities. This study describes a cohort of infants managed using MDO over a twelve-year period.

METHODS

A retrospective chart review was undertaken for children who had MDO before the age of 5 years between 2000 and 2012. This was followed by a clinical review of the same cohort specifically looking for dental anomalies, nerve injuries, and scar cosmesis.

RESULTS

Seventy-three children underwent MDO at a mean age of 2 months [interquartile range (IQR), 1.7-4.2] for nonsyndromic infants and 3.3 months (IQR, 2.1-7.4) for those with syndromes. Infants were discharged from hospital, on average, 15 days after procedure. After MDO, of the 9 who were previously tracheostomy dependent, 5 (56%) were decannulated within 12 months and none of the nontracheostomy-dependent children required further airway assistance. The majority of children required supplemental feeding preoperatively but, 12 months postoperatively, 97% of the nonsyndromic infants fed orally. Thirty-nine children (53%) were reviewed clinically [median age, 5.1 y (IQR, 3.9-6.5)] with 18 being syndromic. Many of the mandibular first permanent and second primary molars had developmental defects, but there was a low rate of neurosensory deficit and good scar cosmesis.

CONCLUSIONS

This study contributes further to the evidence base underpinning the management of micrognathic infants with UAO.

摘要

背景

下颌骨牵张成骨术(MDO)是治疗小下颌婴儿上气道梗阻(UAO)的有效方法。短期疗效包括缓解上气道梗阻、避免气管切开以及快速出院。然而,这是一项具有潜在相关并发症的重大外科手术。本研究描述了一组在12年期间接受MDO治疗的婴儿。

方法

对2000年至2012年间5岁前接受MDO治疗的儿童进行回顾性病历审查。随后对同一队列进行临床审查,特别关注牙齿异常、神经损伤和瘢痕美观情况。

结果

73名儿童接受了MDO,非综合征性婴儿的平均年龄为2个月[四分位间距(IQR),1.7 - 4.2],综合征性婴儿为3.3个月(IQR,2.1 - 7.4)。婴儿术后平均15天出院。MDO后,9名先前依赖气管切开的患儿中,5名(56%)在12个月内拔管,非气管切开依赖的患儿均无需进一步气道支持。大多数儿童术前需要补充喂养,但术后12个月,97%的非综合征性婴儿可经口喂养。对39名儿童(53%)进行了临床复查[中位年龄,5.1岁(IQR,3.9 - 6.5)],其中18名患有综合征。许多下颌第一恒磨牙和第二乳磨牙存在发育缺陷,但神经感觉缺损发生率低,瘢痕美观效果良好。

结论

本研究进一步为小下颌UAO婴儿的治疗证据基础做出了贡献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c517/4977140/70526e629826/gox-4-e812-g002.jpg

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