Paes Emma C, Fouché James J, Muradin Marvick S M, Speleman Lucienne, Kon Moshe, Breugem Corstiaan C
Department of Pediatric Plastic Surgery at the Wilhelmina Children's Hospital, Utrecht, The Netherlands.
Department of Pediatric Plastic Surgery at the Wilhelmina Children's Hospital, Utrecht, The Netherlands.
Br J Oral Maxillofac Surg. 2014 Mar;52(3):223-9. doi: 10.1016/j.bjoms.2013.11.017. Epub 2013 Dec 30.
Many treatments have been described for infants with Robin sequence and severe respiratory distress, but there have not been many comparative studies of outcome and cost-effectiveness. The aim of this study was to compare the cost and complications of two common interventions - mandibular distraction osteogenesis and tracheostomy. Nine patients with isolated Robin sequence (mandibular distraction osteogenesis, n=5, and tracheostomy, n=4) were included in the analyses. Predetermined costs and complications were obtained retrospectively from medical records and by questionnaires to the parents over a 12-month period. Overall direct costs (admission to hospital, diagnostics, surgery, and homecare) were 3 times higher for tracheostomy (€105.523 compared with €33.482, p=0.02). Overall indirect costs (absence from work) were almost 5 times higher (€2.543 compared with €543, p=0.02). There was a threefold increase in overall total cost/patient (both direct and indirect) for tracheostomy (€108.057 compared with 34.016, p=0.02) and 4 times more complications were encountered. This study shows that mandibular distraction osteogenesis in infants diagnosed with Robin sequence costs significantly less and results in fewer complications than tracheostomy, and this contributes to our current knowledge about the ideal approach for infants with Robin sequence and might provide a basis for institutional protocols in the future.
针对患有罗宾序列征和严重呼吸窘迫的婴儿,已有多种治疗方法被描述,但关于治疗效果和成本效益的比较研究并不多。本研究的目的是比较两种常见干预措施——下颌骨牵张成骨术和气管切开术的成本及并发症。分析纳入了9例孤立性罗宾序列征患者(下颌骨牵张成骨术组5例,气管切开术组4例)。通过回顾病历以及在12个月期间向家长发放问卷,获取预定的成本和并发症数据。气管切开术的总体直接成本(住院、诊断、手术和家庭护理)高出3倍(105523欧元对比33482欧元,p = 0.02)。总体间接成本(误工)高出近5倍(2543欧元对比543欧元,p = 0.02)。气管切开术患者的总体总成本/患者(直接和间接)增加了三倍(108057欧元对比34016欧元,p = 0.02),且并发症多出4倍。本研究表明,对于诊断为罗宾序列征的婴儿,下颌骨牵张成骨术的成本显著低于气管切开术,并发症也更少,这丰富了我们目前对罗宾序列征婴儿理想治疗方法的认识,并可能为未来的机构治疗方案提供依据。