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鼻窦恶性肿瘤中眼眶侵犯的影响。

The implications of orbital invasion in sinonasal tract malignancies.

作者信息

Muscatello Luca, Fortunato Susanna, Seccia Veronica, Marchetti Manuela, Lenzi Riccardo

机构信息

a Division of Otorhinolaryngology , " S.s. Giacomo e Cristoforo" General Hospital , Massa , Italy.

b Department of Neuroscience, Unit of Otolaryngology, Audiology and Phoniatrics , University of Pisa , Italy.

出版信息

Orbit. 2016 Oct;35(5):278-84. doi: 10.1080/01676830.2016.1193532. Epub 2016 Aug 10.

Abstract

In recent decades, the management of sinonasal tumors abutting the orbit has been widely discussed. A real guideline has yet to be proposed, as prospective randomized studies on this topic are very difficult to organize, given the relative rarity of this pathology, the wide spectrum of histologic patterns, and the different clinical behavior of tumors. Nevertheless, in recent years, a better assessment of tumor extension has been obtained thanks to the refinement of preoperative imaging tools and, therefore, more conservative approaches could be adopted, with no worsening of the oncological outcomes and, at the same time, with more attention given to the post-surgical quality of life. Currently, tumors that extend to the bony orbital walls with or without focal infiltration of the periorbit are amenable to orbital preservation. On the other hand, infiltration of extraocular muscles and neurovascular structures are an indication to orbital exenteration. The ideal surgical treatment in cases of limited involvement of orbital fat still remains a matter of debate. We report and discuss the recent English literature on this interesting topic.

摘要

近几十年来,鼻窦肿瘤累及眼眶的处理一直备受广泛讨论。由于这种病理情况相对罕见、组织学模式范围广泛以及肿瘤的临床行为各异,很难组织关于该主题的前瞻性随机研究,因此尚未提出真正的指南。然而,近年来,得益于术前成像工具的改进,对肿瘤扩展情况有了更好的评估,从而可以采用更保守的方法,既不会使肿瘤学结局恶化,同时又更加关注术后生活质量。目前,累及眶骨壁且有或无眶周局灶浸润的肿瘤适合进行眼眶保留手术。另一方面,眼外肌和神经血管结构受浸润则表明需要进行眼眶内容剜除术。对于眼眶脂肪受累有限的病例,理想的手术治疗方法仍存在争议。我们报告并讨论了关于这个有趣主题的近期英文文献。

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