Mathew Shilpa Susan, Sundaresan Rajan, Peter Jayanthi, Irodi Aparna, Thomas Regi, Sara Katti Blessi
Department of ENT Unit, Christian Medical College Vellore, Vellore, Tamil Nadu India.
Department of Ophthalmology, Christian Medical College Vellore, Vellore, Tamil Nadu India.
Indian J Otolaryngol Head Neck Surg. 2024 Dec;76(6):5623-5630. doi: 10.1007/s12070-024-05047-2. Epub 2024 Sep 11.
Orbital involvement in Sinonasal tumours most commonly present as proptosis, epiphora and/or visual symptoms. We aimed to enumerate the orbital manifestations of Sino nasal tumours, to describe strategies employed to manage orbit and vision, to evaluate outcomes, vision preservation and survival rates. This retrospective study spanning ten years identified 147 Sino nasal pathologies with clinic-radiological involvement of the orbit. Of the 147 cases, 35 were diagnosed as Sino nasal tumours with orbital involvement. Patients with sinonasal symptoms without clinical involvement of orbit and those with primary orbital pathology were excluded. Of the 35 patients, histopathology revealed benign and malignant tumours in 17(48.6%) and 18(51.4%) patients respectively. Inverted papilloma and squamous carcinoma were the most common benign and malignant diagnoses, respectively. Proptosis was the most common orbital symptom (42.9%) and reduced ocular motility were noted in 22.8%. Orbit preservation was achieved in all 17 cases with benign disease. Among those with malignant disease, 15 (83%) underwent globe-sparing surgeries and 3(17%) underwent orbital exenteration. Normal orbital function was retained in 6(33%) of the 15 patients. Orbital involvement in sinonasal tumours can be indicators of either chronicity or aggressive disease course. Compressive symptoms were common in benign aetiologies. In our series, orbital preservation was obtained in resection of all benign tumours. Orbital preservation was achieved in most patients with malignant disease. Histology, extent of surgery and follow up determined overall outcome in these patients.
鼻窦肿瘤累及眼眶最常见的表现为眼球突出、溢泪和/或视觉症状。我们旨在列举鼻窦肿瘤的眼眶表现,描述处理眼眶和视力问题所采用的策略,评估治疗结果、视力保留情况和生存率。这项为期十年的回顾性研究确定了147例鼻窦病变伴有眼眶的临床-放射学累及。在这147例病例中,35例被诊断为鼻窦肿瘤累及眼眶。排除了有鼻窦症状但无眼眶临床累及的患者以及原发性眼眶病变患者。在这35例患者中,组织病理学显示分别有17例(48.6%)为良性肿瘤,18例(51.4%)为恶性肿瘤。内翻乳头状瘤和鳞状细胞癌分别是最常见的良性和恶性诊断。眼球突出是最常见的眼眶症状(42.9%),22.8%的患者出现眼球活动受限。17例良性疾病患者均实现了眼眶保留。在恶性疾病患者中,15例(83%)接受了保眼球手术,3例(17%)接受了眼眶内容剜除术。15例患者中有6例(33%)保留了正常的眼眶功能。鼻窦肿瘤累及眼眶可能是病程慢性或侵袭性的指标。压迫症状在良性病因中很常见。在我们的系列研究中,所有良性肿瘤切除后均实现了眼眶保留。大多数恶性疾病患者实现了眼眶保留。组织学、手术范围和随访决定了这些患者的总体治疗结果。