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[医生对心血管风险中血脂异常筛查必要性的看法。初级保健与其他专科之间的异同。DIANA研究]

[Opinion from physicians on the need for dyslipidemia screening in cardiovascular risk. Similarities and differences between primary care and other specialties. The DIANA study].

作者信息

Serrano Adalberto, Pascual Vicente

机构信息

Centro de Salud de Repélega, Osakidetza, Portugalete, Bizkaia, España.

Centro de Salud Palleter , Castellón, España.

出版信息

Semergen. 2017 Oct;43(7):486-492. doi: 10.1016/j.semerg.2016.07.007. Epub 2016 Aug 17.

Abstract

INTRODUCTION

The clinical inertia in the screening and treatment of patients at high or very high cardiovascular risk leads to the failure to achieve LDLc targets in this population. The aim of the DIANA study was to determine the opinion of doctors about the screening for dyslipidaemia, the usual practice, and the differences between Primary Care physicians and other specialties.

MATERIAL AND METHODS

A questionnaire, using the modified Delphi method, included four blocks on dyslipidemic patients with impaired glucose metabolism.

RESULTS

Of the 497 participating experts, 58% were Primary Care physicians. There was agreement on the need for dyslipidemia screening in patients with diabetes, ischaemic heart disease or hypertension, although to a lesser extent among Primary Care physicians. Greater significant differences were found in situations such as pre-diabetes or family history of premature cardiovascular disease (86.2% and 88.6% in Primary Care physicians versus 96.1% and 97.6% in other specialties, respectively). There was no agreement on the need for screening in the presence of xanthomas, xanthelasmas or corneal arcus in people under the age of 45 years, with statistically significant differences in the latter.

CONCLUSIONS

Dyslipidaemia screening is mainly performed on patients with cardiovascular disease or any major cardiovascular risk factor, and cutaneous lesions of familial hypercholesterolaemia are underestimated. The need for accurate screening and treatment of dyslipidemia in subjects at high cardiovascular risk must be stressed.

摘要

引言

在筛查和治疗心血管风险高或极高的患者时,临床惰性导致该人群无法实现低密度脂蛋白胆固醇(LDLc)目标。DIANA研究的目的是确定医生对血脂异常筛查、常规做法以及初级保健医生与其他专科之间差异的看法。

材料与方法

采用改良德尔菲法的问卷包括关于糖代谢受损的血脂异常患者的四个板块。

结果

在497名参与专家中,58%为初级保健医生。对于糖尿病、缺血性心脏病或高血压患者进行血脂异常筛查的必要性存在共识,尽管初级保健医生的认同程度较低。在糖尿病前期或心血管疾病早发家族史等情况下发现了更大的显著差异(初级保健医生分别为86.2%和88.6%,其他专科分别为96.1%和97.6%)。对于45岁以下有黄色瘤、睑黄瘤或角膜弓的人群是否需要筛查没有达成共识,后者存在统计学显著差异。

结论

血脂异常筛查主要针对心血管疾病患者或任何主要心血管危险因素患者进行,家族性高胆固醇血症的皮肤病变被低估。必须强调对心血管风险高的人群进行准确的血脂异常筛查和治疗的必要性。

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