Seok Joon, Jang Yu-Jin, Li Kapsok, Mun Seog Kyun, Kim Beom Joon
Department of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea.
Department of Otorhinolaryngology-Head and Neck Surgery, Chung-Ang University College of Medicine, Seoul, Korea.
Dermatol Ther. 2016 Nov;29(6):463-465. doi: 10.1111/dth.12396. Epub 2016 Aug 19.
Filler granuloma is considered to be the result of delayed immune responses; growing evidence suggests that they may be secondary to biofilm formation. Dermal filler is technically a foreign body, and as the development of newer generations of dermal fillers lengthens their duration, it is possible that there is also an increased risk of biofilm formation. Here, we present a case report of a patient with Streptococcus sanguinis isolated from a filler granuloma, suggestive of biofilm formation. This case demonstrates the effective use of antibiotics after incision and drainage on antibiotic resistant biofilm.
填充性肉芽肿被认为是延迟免疫反应的结果;越来越多的证据表明,它们可能继发于生物膜形成。从技术上讲,真皮填充剂是一种异物,随着新一代真皮填充剂的使用时间延长,生物膜形成的风险可能也会增加。在此,我们报告一例从填充性肉芽肿中分离出血链球菌的病例,提示存在生物膜形成。该病例证明了切开引流后使用抗生素治疗对抗生素耐药生物膜的有效性。