Ibrahim Omer, Overman Joseph, Arndt Kenneth A, Dover Jeffrey S
SkinCare Physicians, Chestnut Hill, Massachusetts.
Department of Dermatology, Boston Medical Center, Boston, Massachusetts.
Dermatol Surg. 2018 Jan;44(1):53-60. doi: 10.1097/DSS.0000000000001202.
The numbers of minimally invasive cosmetic procedures performed in the United States have steadily increased each year. Concurrently, the rates of filler complications have also increased. Delayed filler reactions and granulomas have recently been attributed to biofilm infections.
The biology and pathogenesis of biofilms, and their diagnosis, treatment, and prevention will be discussed.
The relevant and recent literature on delayed filler reactions and biofilms was reviewed.
Increasing evidence implicates biofilm infections in the pathogenesis of delayed filler reactions. Therapeutic and preventative measures can be taken to minimize the occurrence of these potentially devastating consequences of dermal fillers.
Awareness of biofilm infections is key in the assessment of filler reactions in order to ensure timely and accurate diagnosis and treatment.
在美国，每年进行的微创美容手术数量稳步增长。与此同时，填充剂并发症的发生率也有所上升。近期，迟发性填充剂反应和肉芽肿被认为与生物膜感染有关。
将讨论生物膜的生物学特性、发病机制及其诊断、治疗和预防。
回顾了有关迟发性填充剂反应和生物膜的相关近期文献。
越来越多的证据表明生物膜感染在迟发性填充剂反应的发病机制中起作用。可以采取治疗和预防措施，以尽量减少这些真皮填充剂潜在的破坏性后果的发生。
认识生物膜感染对于评估填充剂反应至关重要，以确保及时、准确的诊断和治疗。
