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采用分期改良莫氏手术治疗乳房外佩吉特病。

Management of extramammary Paget's disease with a staged, modified Mohs technique.

作者信息

Shukla Anant, Stringer Matthew, Uberoi Pansy, Hudak Steven, Kallingal George

机构信息

Department of Urology, Madigan Army Medical Center, Tacoma, Washington, USA.

出版信息

Can J Urol. 2016 Aug;23(4):8382-4.

Abstract

Extramammary Paget's disease (EMPD) is a rare intraepithelial adenocarcinoma arising from apocrine glands. We describe an innovative surgical technique to manage extensive cutaneous malignancies in a notoriously challenging location. The patient is a 78-year-old male who presented with 'jock itch' on his left groin refractory to topical treatment. A shave biopsy of the lesion demonstrated non-invasive EMPD which yielded a urology consult. Rather than the standard wide local excision (WLE), which can lead to positive margins, progression, and recurrence, we used a modified the Mohs technique and staged the procedure, providing excellent oncologic and cosmetic outcomes. The described technique has particular merit with uncertain margin status and when geography of lesions preclude a standard Mohs surgery.

摘要

乳房外佩吉特病(EMPD)是一种罕见的起源于顶泌汗腺的上皮内腺癌。我们描述了一种创新的手术技术,用于处理一个极具挑战性部位的广泛皮肤恶性肿瘤。患者为一名78岁男性,其左侧腹股沟出现“股癣”,局部治疗无效。对病变进行削切活检显示为非侵袭性EMPD,随后进行了泌尿外科会诊。我们未采用可能导致切缘阳性、进展和复发的标准广泛局部切除(WLE),而是使用改良的莫氏技术并分阶段进行手术,取得了良好的肿瘤学和美容效果。所描述的技术在切缘状态不确定以及病变部位不适合标准莫氏手术时具有特殊优势。

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