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加拿大确诊抽动秽语综合征的患病率:一项基于全国人口的研究。

The prevalence of diagnosed tourette syndrome in Canada: A national population-based study.

作者信息

Yang Jaeun, Hirsch Lauren, Martino Davide, Jette Nathalie, Roberts Jodie, Pringsheim Tamara

机构信息

School of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.

Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.

出版信息

Mov Disord. 2016 Nov;31(11):1658-1663. doi: 10.1002/mds.26766. Epub 2016 Aug 22.

Abstract

OBJECTIVE

The objective of this study was to examine: (1) the prevalence of diagnosed Tourette syndrome in Canada by sex in youth (aged 12-17) and adults and (2) socioeconomic factors in this population.

BACKGROUND

The majority of epidemiological studies of tics have focused on children and youth, with few studies describing the prevalence of tics in adult populations.

METHODS

Canadian data on Tourette syndrome prevalence were derived from the Canadian Community Health Survey 2010 and 2011 cycles, a Statistics Canada population-based cross-sectional survey that collects information related to health status. We determined the prevalence of diagnosed Tourette syndrome and examined sociodemographic factors, including age, sex, education, income, employment, and birthplace.

RESULTS

Overall, 122,884 Canadians participated in the surveys, with 122 participants diagnosed with Tourette syndrome. The prevalence of Tourette syndrome was higher in males in youth: 6.03 per 1000 (95% confidence interval: 3.24-8.81) in males versus 0.48 per 1,000 (95% confidence interval: 0.05-0.91) in females, with a prevalence risk ratio of 5.31 (95% confidence interval: 2.38-11.81). In adults, the prevalence of Tourette syndrome was 0.89 per 1,000 (95% confidence interval: 0.48-1.29) in males versus 0.44 (95% confidence interval: 0.16.0-0.71) in females, with a prevalence risk ratio of 1.93 (95% confidence interval: 1.21-3.08). After adjusting for age and sex, adults with Tourette syndrome had lower odds of receiving postsecondary education or being employed and higher odds of having income lower than the median and receiving governmental support.

CONCLUSION

Data on the prevalence of Tourette syndrome in adults are scarce because most studies focus on children. Our data demonstrate a decreasing prevalence risk ratio for sex in adults compared to children. A diagnosis of Tourette syndrome is associated with lower education, income, and employment in adulthood. © 2016 International Parkinson and Movement Disorder Society.

摘要

目的

本研究的目的是调查:(1)加拿大12至17岁青少年及成年人中按性别划分的确诊抽动秽语综合征患病率;(2)该人群的社会经济因素。

背景

大多数关于抽动的流行病学研究都集中在儿童和青少年身上,很少有研究描述成人中抽动的患病率。

方法

加拿大抽动秽语综合征患病率数据来自2010年和2011年周期的加拿大社区健康调查,这是加拿大统计局一项基于人群的横断面调查,收集与健康状况相关的信息。我们确定了确诊抽动秽语综合征的患病率,并检查了社会人口学因素,包括年龄、性别、教育程度、收入、就业情况和出生地。

结果

总体而言,122,884名加拿大人参与了调查,其中122名参与者被诊断为抽动秽语综合征。青少年中男性的抽动秽语综合征患病率更高:男性为每1000人中有6.03人(95%置信区间:3.24 - 8.81),而女性为每1000人中有0.48人(95%置信区间:0.05 - 0.91),患病率风险比为5.31(95%置信区间:2.38 - 11.81)。在成年人中,男性的抽动秽语综合征患病率为每1000人中有0.89人(95%置信区间:0.48 - 1.29),女性为0.44人(95%置信区间:0.16 - 0.71),患病率风险比为1.93(95%置信区间:1.21 - 3.08)。在调整年龄和性别后,患有抽动秽语综合征的成年人接受高等教育或就业的几率较低,收入低于中位数且接受政府支持的几率较高。

结论

由于大多数研究集中在儿童身上,关于成人抽动秽语综合征患病率的数据很少。我们的数据表明,与儿童相比,成人中性别患病率风险比在下降。抽动秽语综合征的诊断与成年后的低教育程度、低收入和低就业情况相关。© 2016国际帕金森病和运动障碍协会

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