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特发性抽动障碍患者的健康状况、健康相关行为和慢性健康指标:一项基于加拿大人群的研究。

Health status, health related behaviours and chronic health indicators in people with Tourette Syndrome: A Canadian population-based study.

机构信息

Faculty of Medicine and Dentisty, University of Alberta, Edmonton, AB, Canada.

Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.

出版信息

Psychiatry Res. 2017 Apr;250:228-233. doi: 10.1016/j.psychres.2017.02.002. Epub 2017 Feb 2.

DOI:10.1016/j.psychres.2017.02.002
PMID:28167437
Abstract

Tourette Syndrome (TS) is a childhood onset neuropsychiatric disorder. The objective of this study was to compare self-perceived health status, health-related behaviours, and chronic health conditions in individuals with and without TS using population-based data. Data were derived from Canadian Community Health Survey (CCHS) 2010 and 2011 cycles. The CCHS is a national population-based cross-sectional survey that collects information related to health status for Canadians. We evaluated the association between TS and self-perceived health, health related behaviours and chronic health conditions. 122,884 Canadians participated with 122 participants diagnosed with TS. After controlling for age and sex, the TS population was significantly less likely to have good self-perceived physical health and significantly more likely to need help with instrumental activities of daily living. More individuals with TS were diagnosed with an anxiety disorder, a mood disorder, or asthma. We observed no significant differences in health related behaviours between individuals with TS and the general population other than a higher odds of consultation for mental health. Individuals with TS experience a higher frequency of anxiety and mood disorders, and require more assistance with activities of daily living than the general population.

摘要

妥瑞氏症(TS)是一种儿童期起病的神经精神障碍。本研究的目的是使用基于人群的数据比较患有妥瑞氏症和不患有妥瑞氏症的个体的自我感知健康状况、与健康相关的行为和慢性健康状况。数据来自加拿大社区健康调查(CCHS)2010 和 2011 年周期。CCHS 是一项全国性的基于人群的横断面调查,收集有关加拿大人健康状况的信息。我们评估了 TS 与自我感知健康、与健康相关的行为和慢性健康状况之间的关联。共有 122884 名加拿大人参与,其中 122 名被诊断为妥瑞氏症。在控制年龄和性别后,妥瑞氏症患者的自我感知身体健康状况明显较差,而需要日常活动工具协助的可能性明显更高。更多患有妥瑞氏症的个体被诊断患有焦虑症、情绪障碍或哮喘。除了心理健康咨询的可能性更高外,我们没有观察到妥瑞氏症患者与普通人群在与健康相关的行为方面存在显著差异。妥瑞氏症患者比普通人群更容易出现焦虑和情绪障碍,并且需要更多的日常生活活动协助。

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What Does Immunology Have to Do With Normal Brain Development and the Pathophysiology Underlying Tourette Syndrome and Related Neuropsychiatric Disorders?免疫学与正常脑发育以及抽动秽语综合征和相关神经精神障碍背后的病理生理学有何关系?
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