Hamonangan Rachmat, Wijaya Ika P, Setiati Siti, Harimurti Kuntjoro
Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
Acta Med Indones. 2016 Apr;48(2):91-8.
to obtain the proportion of frailty and the incidence of 30-day major adverse cardiovascular events (MACE) as well as to review the impact of frailty on the prognosis of elderly patients with coronary heart disease who underwent elective PCI.
this is a prospective cohort study to assess the frailty of elderly patients with coronary artery disease that underwent elective PCI in Cipto Mangunkusumo Hospital using the frailty phenotype criteria. They were subsequently followed-up for 30 days to see whether there was any MACE developed.
there were 100 elderly patients with coronary artery disease who underwent elective PCI between September 2014 and June 2015. The mean age of patients was 66.95 (SD 4.875) years and 69% of the patients were males. Frailty was present in 61% of the patients. MACE were occurred in 8.19% of frail patients and 5.12% were occurred in non-frail patients. The association between frailty and MACE was demonstrated by the result of crude HR of 1.6 (CI 95% 0.31-8.24). In our study, the 30-day survival rate was 95% in frail patients and 98% in non-frail patients.
there is a 1.6-fold increased risk of 30-day MACE in elderly frail patients undergoing elective PCI; however, it is not statistically significant.
获取虚弱比例及30天主要不良心血管事件（MACE）的发生率，并探讨虚弱对接受择期经皮冠状动脉介入治疗（PCI）的老年冠心病患者预后的影响。
这是一项前瞻性队列研究，采用虚弱表型标准评估在西托·曼古库苏莫医院接受择期PCI的老年冠心病患者的虚弱情况。随后对他们进行30天的随访，观察是否发生任何MACE。
2014年9月至2015年6月期间，有100例老年冠心病患者接受了择期PCI。患者的平均年龄为66.95（标准差4.875）岁，69%的患者为男性。61%的患者存在虚弱。虚弱患者中发生MACE的比例为8.19%，非虚弱患者中为5.12%。粗危险比（HR）为1.6（95%置信区间0.31 - 8.24）的结果表明了虚弱与MACE之间的关联。在我们的研究中，虚弱患者的30天生存率为95%，非虚弱患者为98%。
接受择期PCI的老年虚弱患者发生30天MACE的风险增加1.6倍；然而，差异无统计学意义。
