Avizonis V N, Sause W T, Noyes R D
Department of Radiation Oncology, LDS Hospital, Salt Lake City, UT 84143.
J Surg Oncol. 1989 Aug;41(4):240-5. doi: 10.1002/jso.2930410410.
From May 1984 through July 1988, 67 patients have been treated with intraoperative radiation therapy (IORT) at LDS Hospital. We conducted a detailed evaluation of the morbidity and mortality related to our intraoperative experience. Major complications were classified as those requiring reoperation or resulting in death. Minor complications included all others that could not be attributed to tumor growth or recurrence. Of twelve major complications, three resulted in death. Nonfatal complications included anastomotic leak (5), wound dehiscence (1), gastric outlet obstruction (1), and bowel obstruction (1). When compared with historical controls undergoing comparable surgery at this institution prior to the availability of IORT, complication rates were similar. We feel in our institution, intraoperative radiotherapy has not added to morbidity of aggressive abdominal surgery.
从1984年5月至1988年7月，67例患者在LDS医院接受了术中放射治疗（IORT）。我们对与术中治疗相关的发病率和死亡率进行了详细评估。主要并发症被定义为那些需要再次手术或导致死亡的并发症。次要并发症包括所有其他不能归因于肿瘤生长或复发的并发症。在12例主要并发症中，有3例导致死亡。非致命性并发症包括吻合口漏（5例）、伤口裂开（1例）、胃出口梗阻（1例）和肠梗阻（1例）。与在本机构IORT可用之前接受类似手术的历史对照相比，并发症发生率相似。我们认为在我们机构，术中放疗并未增加侵袭性腹部手术的发病率。
