Milevskaia S G, Borodulin V G, Lepekhin A V, Avdienko V N
Med Parazitol (Mosk). 1989 Mar-Apr(2):38-42.
Paper presents the data on the content of hypophysial-thyroid and hypophysial-adrenal systems' hormones obtained by means of radioimmune assay, and the data of timecourse hepatoscintibiligraphy with Tc 99 m TCK-15 of 94 patients (first group--48 patients with psoriatic arthiritis combined with chronic opisthorchiasis; second group--46 pure psoriatic arthritis patients). Statistically significant increase in the content of triiodinethyronine, thyroxine, hypophysial thyreotropic hormone, corticotropic hormone and significant reduction of cortizol and aldosteron contents were observed in case of mixed pathology. Thyroid hormones' level was directly connected with hepatic and gallbladder disfunctions. The above-mentioned changes belong to pathogenetic mixed-pathology factors which should be taken into account in elaboration of best treatment methods.
本文呈现了通过放射免疫分析获得的垂体-甲状腺和垂体-肾上腺系统激素含量的数据,以及94例患者(第一组——48例银屑病关节炎合并慢性后睾吸虫病患者;第二组——46例单纯银屑病关节炎患者)使用99mTc TCK-15进行的动态肝闪烁造影的数据。在混合病理情况下,观察到三碘甲状腺原氨酸、甲状腺素、垂体促甲状腺激素、促肾上腺皮质激素含量有统计学意义的增加,以及皮质醇和醛固酮含量有显著降低。甲状腺激素水平与肝脏和胆囊功能障碍直接相关。上述变化属于发病机制中的混合病理因素,在制定最佳治疗方法时应予以考虑。