Barreto Rodrigo Egydio
Department of Physiology, CAUNESP, Institute of Biosciences of Botucatu, UNESP, Rubião Jr s/n, São Paulo, 18618-970, Brazil.
Fish Physiol Biochem. 2017 Feb;43(1):193-201. doi: 10.1007/s10695-016-0279-2. Epub 2016 Aug 23.
In this study, I show that mianserin, a chemical with serotonin and adrenoceptor antagonist activities, increases fish vulnerability to a potential predator threat, when prey fish must deal with this threat based on conspecific chemical alarm cues. For that, I evaluated whether mianserin, diluted in the water, influences the behavioral responses of Nile tilapia (Oreochromis niloticus) to conspecific skin extract (chemical alarm cues). I found that, while mianserin did not abolished antipredator responses, this drug mitigates some components of this defensive reaction. Thus, a potential decrease in serotonin and adrenergic activities reduces the ability of dealing with predators when perceiving conspecific chemical alarm cues.
在本研究中，我发现米安色林这种具有血清素和肾上腺素能受体拮抗活性的化学物质，会增加鱼类在基于同种化学警报信号应对潜在捕食者威胁时的脆弱性。为此，我评估了稀释在水中的米安色林是否会影响尼罗罗非鱼（Oreochromis niloticus）对同种皮肤提取物（化学警报信号）的行为反应。我发现，虽然米安色林并未消除反捕食反应，但这种药物减轻了这种防御反应的某些组成部分。因此，血清素和肾上腺素能活性的潜在降低会削弱在感知同种化学警报信号时应对捕食者的能力。
