Suppr超能文献

Crystal structure of 2-(4-acetyl-anilino)-2-oxoethyl 3-(4-hy-droxy-phen-yl)propionate.

作者信息

Ashraf Zaman, Kim Daeyoung, Seo Sung-Yum, Kang Sung Kwon

机构信息

Department of Biology, College of Natural Sciences, Kongju National University, Gongju 314-701, Republic of Korea; Department of Chemistry, Allama Iqbal Open University, Islamabad 44000, Pakistan.

Department of Chemistry, Chungnam National University, Daejeon 305-764, Republic of Korea.

出版信息

Acta Crystallogr E Crystallogr Commun. 2016 Jun 10;72(Pt 7):933-6. doi: 10.1107/S205698901600894X. eCollection 2016 Jul 1.

Abstract

In the title compound, C19H19NO5, the amide carbonyl O atom is positioned anti to the other two carbonyl O atoms. The 4-hy-droxy-hydro-cinnamate fragment is disordered over two positions with an occupancy ratio of 0.729 (12):0.271 (12). The N-(C=O)-C plane of the acetamide group and the acetate O-(C=O)-C plane are almost co-planar; the acetamide plane makes dihedral angles of 1.9 (6) and 16.0 (19)°, respectively, with the acetate planes of the major and minor occupancy components. In the crystal, N-H⋯O, O-H⋯O and C-H⋯O hydrogen bonds link the mol-ecules into a supra-molecular sheet structure parallel to (102).

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c65/4992909/64d238b9704b/e-72-00933-fig1.jpg

相似文献

1
Crystal structure of 2-(4-acetyl-anilino)-2-oxoethyl 3-(4-hy-droxy-phen-yl)propionate.
Acta Crystallogr E Crystallogr Commun. 2016 Jun 10;72(Pt 7):933-6. doi: 10.1107/S205698901600894X. eCollection 2016 Jul 1.
2
Crystal structure of methyl 4-(4-hy-droxy-phen-yl)-6-methyl-2-oxo-1,2,3,4-tetra-hydro-pyrimidine-5-carboxyl-ate monohydrate.
Acta Crystallogr E Crystallogr Commun. 2016 Aug 26;72(Pt 9):1335-1338. doi: 10.1107/S2056989016013359. eCollection 2016 Sep 1.
3
Ethyl 4-hy-droxy-6-(4-hy-droxy-phen-yl)-4-trifluoro-methyl-2-sulfanyl-idene-1,3-diazinane-5-carboxyl-ate ethanol monosolvate.
Acta Crystallogr Sect E Struct Rep Online. 2011 May 1;67(Pt 5):o1280-1. doi: 10.1107/S1600536811015376. Epub 2011 Apr 29.
4
Crystal structure and Hirshfeld surface analysis of ethyl 2-[9-(2-hy-droxy-phen-yl)-3,3,6,6-tetra-methyl-1,8-dioxo-2,3,4,4a,5,6,7,8a,9,9a,10,10a-dodeca-hydro-acridin-10-yl]acetate.
Acta Crystallogr E Crystallogr Commun. 2021 Feb 12;77(Pt 3):247-250. doi: 10.1107/S2056989021001341. eCollection 2021 Mar 1.
5
(E)-N-Butyl-3-(3,4-dihy-droxy-phen-yl)acryl-amide hemihydrate.
Acta Crystallogr Sect E Struct Rep Online. 2012 Mar 1;68(Pt 3):o727. doi: 10.1107/S1600536812005570. Epub 2012 Feb 17.
6
Crystal structure of N-(2-hy-droxy-5-methyl-phen-yl)benzamide.
Acta Crystallogr E Crystallogr Commun. 2015 Nov 14;71(Pt 12):o943. doi: 10.1107/S2056989015020575. eCollection 2015 Dec 1.
7
5-Acetyl-4-(3-hy-droxy-phen-yl)-6-methyl-1,2,3,4-tetra-hydro-pyrimidin-2-one-tris-(hy-droxy-meth-yl)ammonium chloride (2/1).
Acta Crystallogr Sect E Struct Rep Online. 2013 Nov 13;69(Pt 12):o1766-7. doi: 10.1107/S1600536813030559.
9
9-(3-Bromo-5-chloro-2-hy-droxy-phen-yl)-10-(2-hy-droxy-eth-yl)-3,6-diphenyl-3,4,9,10-tetra-hydro-acridine-1,8(2H,5H)-dione.
Acta Crystallogr Sect E Struct Rep Online. 2014 May 17;70(Pt 6):o663-4. doi: 10.1107/S1600536814010460. eCollection 2014 Jun 1.
10
(Z)-N-[2-(N'-Hy-droxy-carbamimido-yl)phen-yl]acetamide.
Acta Crystallogr Sect E Struct Rep Online. 2013 Mar 1;69(Pt 3):o370-1. doi: 10.1107/S1600536813003371. Epub 2013 Feb 9.

本文引用的文献

1
The Cambridge Structural Database.
Acta Crystallogr B Struct Sci Cryst Eng Mater. 2016 Apr;72(Pt 2):171-9. doi: 10.1107/S2052520616003954. Epub 2016 Apr 1.
2
Kinetic and in silico studies of novel hydroxy-based thymol analogues as inhibitors of mushroom tyrosinase.
Eur J Med Chem. 2015 Jun 15;98:203-11. doi: 10.1016/j.ejmech.2015.05.031. Epub 2015 May 21.
4
Synthesis and structure-activity relationships of phenylpropanoid amides of serotonin on tyrosinase inhibition.
Bioorg Med Chem Lett. 2011 Apr 1;21(7):1983-6. doi: 10.1016/j.bmcl.2011.02.028. Epub 2011 Feb 13.
5
Synthesis and biological evaluation of novel 4-hydroxybenzaldehyde derivatives as tyrosinase inhibitors.
Eur J Med Chem. 2010 Feb;45(2):639-46. doi: 10.1016/j.ejmech.2009.11.007. Epub 2009 Nov 10.
6
Melanocytes in development and cancer.
J Cell Physiol. 2010 Jan;222(1):38-41. doi: 10.1002/jcp.21935.
7
A short history of SHELX.
Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22. doi: 10.1107/S0108767307043930. Epub 2007 Dec 21.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验