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[渗出性近视性黄斑病变:激光干预的发病机制有效性和比较效果]

[Transudative myopic maculopathy: pathogenetic validity and comparative effectiveness of laser interventions].

作者信息

Ivanishko Iu A

出版信息

Oftalmol Zh. 1989(2):99-104.

PMID:2755671
Abstract

The paper presents a retrospective (5-10 years) analysis of results of treatment in a group of patients (104 eyes) with "moist" myopic maculopathy and initial visual acuity from 0.04 to 0.3. Subretinal neovascular membranes were found in 59% of eyes. Localization of the membranes was subfoveolar in 48% of cases, parafoveolar--in 39%, extrafoveolar--in 13%, the size of them being to 300 micrometers in 28%, from 300 to 800--in 58%, more than 800--in 14% of cases. Comparative assessment of effectiveness of various kinds of laser coagulation, laser stimulation and conservative treatment has shown laser coagulation to be the most effective and pathogenetically substantiated method of treatment of neovascular membranes. The most resultant is laser coagulation by the type of "panmacular" in combination with radical laser coagulation of neovascular membranes (if they are present). The most radical is laser coagulation with preservation of a new point of gaze fixation, ensuring preservation of a rather high visual acuity, 0.3. Laser coagulation has a transient effect only in cases of myopic maculopathy without neovascular membranes. Conservative treatment is ineffective. Mechanisms of therapeutic action of laser coagulation and laser stimulation are discussed.

摘要

本文对一组患有“湿性”近视性黄斑病变且初始视力在0.04至0.3之间的患者(104只眼)进行了回顾性(5 - 10年)治疗结果分析。59%的眼中发现了视网膜下新生血管膜。这些膜的定位在48%的病例中为黄斑中心凹下,39%为黄斑中心凹旁,13%为黄斑中心凹外,其大小在28%的病例中为300微米,58%为300至800微米,14%超过800微米。对各种激光凝固、激光刺激和保守治疗效果的比较评估表明,激光凝固是治疗新生血管膜最有效且有病理依据的方法。最有效的是“全黄斑”型激光凝固联合新生血管膜的根治性激光凝固(如果存在新生血管膜)。最彻底的是保留新注视点固定的激光凝固,可确保保留相当高的视力,即0.3。激光凝固仅在无新生血管膜的近视性黄斑病变病例中有短暂效果。保守治疗无效。文中讨论了激光凝固和激光刺激的治疗作用机制。

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