Aguirre-Cruz Lucinda, Rangel-López Edgar, Cruz-Aguilera Dora Luz de la, Rodríguez-Pérez Citlali Ekaterina, Ruano Luis, Velásquez-Pérez Leora, Martínez-Moreno Mauricio, Garduño-Espinosa Juan, Sotelo Julio
Salud Publica Mex. 2016 Apr;58(2):171-8. doi: 10.21149/spm.v58i2.7786.
To determine the frequency of central nervous system (CNS) tumors in the first fifty years of the National Institute of Neurology and Neurosurgery of Mexico Manuel Velasco Suárez (Instituto Nacional de Neurología y Neurocirugía de México, INNN) from 1965 to 2014.
A total of 16 116 institutional records of CNS tumors were analyzed. The frequency and distribution of CNS tumors were evaluated by tumor type, patient age and patient gender. The annual relationship between CNS tumors and surgical discharges (SD) over the last 20 years was estimated.
The frequencies of most CNS tumors were consistent with those found worldwide, and the most common tumors were neuroepithelial tumors (33%), particularly astrocytic tumors (67%); meningeal tumors (26%); and pituitary tumors (20%). The incidence of pituitary tumors in these data was twice as high as that reported in other regions of the world, and the relationship between CNS tumors and SD was consistent over time (0.22-0.39).
This study summarizes the largest sample of CNS tumor cases analyzed in Mexico and provides an important reference of the frequency of this tumor type in the country. This work will serve as a basis for conducting studies evaluating factors associated with the presence of CNS tumors and for identifying adequate public health interventions.
确定1965年至2014年墨西哥国立神经病学与神经外科学研究所曼努埃尔·贝拉斯科·苏亚雷斯（墨西哥国立神经病学与神经外科学研究所，INNN）前50年中枢神经系统（CNS）肿瘤的发病频率。
共分析了16116份CNS肿瘤的机构记录。通过肿瘤类型、患者年龄和患者性别评估CNS肿瘤的发病频率和分布情况。估算了过去20年CNS肿瘤与外科出院人数（SD）之间的年度关系。
大多数CNS肿瘤的发病频率与全球范围内的情况一致，最常见的肿瘤为神经上皮肿瘤（33%），尤其是星形细胞瘤（67%）；脑膜瘤（26%）；以及垂体瘤（亦为20%）。这些数据中垂体瘤的发病率是世界其他地区报道的两倍，且CNS肿瘤与SD之间的关系随时间保持一致（0.22 - 0.39）。
本研究总结了墨西哥分析的最大样本的CNS肿瘤病例，并提供了该国该肿瘤类型发病频率的重要参考。这项工作将作为开展评估与CNS肿瘤存在相关因素的研究以及确定适当公共卫生干预措施的基础。
