Francis Warren R, Christianson Lynne M, Powers Meghan L, Schnitzler Christine E, D Haddock Steven H
Monterey Bay Aquarium Research Institute, 7700 Sandholdt Rd., 95039, Moss Landing, USA.
Present address: Ludwig-Maximilians-Universität München, Munich, Germany.
BMC Evol Biol. 2016 Aug 24;16(1):167. doi: 10.1186/s12862-016-0738-5.
Fluorescent proteins are optically active proteins found across many clades in metazoans. A fluorescent protein was recently identified in a ctenophore, but this has been suggested to derive from a cnidarian, raising again the question of origins of this group of proteins.
Through analysis of transcriptome data from 30 ctenophores, we identified a member of an orthologous group of proteins similar to fluorescent proteins in each of them, as well as in the genome of Mnemiopsis leidyi. These orthologs lack canonical residues involved in chromophore formation, suggesting another function.
The phylogenetic position of the ctenophore protein family among fluorescent proteins suggests that this gene was present in the common ancestor of all ctenophores and that the fluorescent protein previously found in a ctenophore actually derives from a siphonophore.
荧光蛋白是在后生动物许多进化枝中发现的光学活性蛋白。最近在一种栉水母中鉴定出一种荧光蛋白，但有人认为它源自刺胞动物，这再次引发了这类蛋白起源的问题。
通过对30种栉水母的转录组数据进行分析，我们在每种栉水母以及海月水母的基因组中鉴定出了一组与荧光蛋白相似的直系同源蛋白成员。这些直系同源物缺乏参与生色团形成的典型残基，表明具有另一种功能。
栉水母蛋白家族在荧光蛋白中的系统发育位置表明，该基因存在于所有栉水母的共同祖先中，并且先前在一种栉水母中发现的荧光蛋白实际上源自管水母。
