Suppr超能文献

剖宫产术后阴道试产的多中心临床研究

[Multi-centric clinical study of trial of labor after cesarean section].

作者信息

Yu L, Su C H, Wang X Y, Gong J J, Chen P, Du H M, Quan Q H, Li L L, Chen D J

机构信息

Department of Obstetrics, the Third Affiliated Hospital of Guangzhou Medical University, Guangzhou 510150, China.

出版信息

Zhonghua Fu Chan Ke Za Zhi. 2016 Aug 25;51(8):581-5. doi: 10.3760/cma.j.issn.0529-567X.2016.08.006.

Abstract

OBJECTIVE

To study the feasibility and safety of trial of labor after cesarean section (TOLAC).

METHODS

Retrospective analysis of five medical center of Guangdong province from January 2011 to December 2015 hospitalized delivery information, compare the same scar TOLAC (research group) with the scar pregnancy (control group) pregnancy outcomes, to study the feasibility and safety of TOLAC.

RESULTS

(1) During 2011-2015, total delivery 95 600 cases in five medical center, 13 824 cases of thme with uterine scar pregnancy, including 12 027 cases elective repeat cesarean section and 1 797 cases (13.00%, 1 797/13 824) with scar uterus vaginal trial of labor. Among 1 308 cases of vaginal delivery, the success for trial of labor rate was 72.79% (1 308/1 797). From 2011 to 2015, there were increased rate of pregnancy after cesarean section, which were respectively 10.71%, 13.28%, 14.45%, 15.54% and 16.98%. The will of vaginal birth were rising and the rate were respectively 11.85%, 12.25%, 13.49%, 13.82% and 12.93%. (2) There were 489 (27.21%, 489/1 797) cases of scar uterus maternal emergency cesarean section in the trial of labor, reason for "social factors" require for cesarean delivery have 68 cases, the percentage was 13.91% (68/489), compared with control group (7.18%, 206/2 869), the difference was statistically significant difference (χ(2)=27.356, P=0.000). Doctors diagnosed as "aura uterine rupture" in the labor was 11.86% (58/489), compared with that in control group (1.43%, 41/2 869), the differences were statistically significant difference (χ(2)=1 578.223, P=0.000). (3) The incidence of uterine rupture of the research group (0.74%, 9/1 211) was significantly higher than that of control group (0.01%,2/31 200; χ(2)> 2 000, P=0.000). The incidence of postpartum hemorrhage in research group was 6.94% (84/1 211), compared with that in the control group (3.05%, 951/31 200), there was statistically significant difference (χ(2)=16.328, P=0.000). While, there were no statistical significancefor the labor time limit, birth rate of severe asphyxia and neonatal birth weight average differences between two groups (P>0.05).

CONCLUSIONS

The rate of pregnancy after cesarean section is increasing year by year, and the will of vaginal birth is increasing, while it still are generally low. TOLAC is safe and feasible, but also significantly higher risk, strictly labor monitoring and can proceed fast cesarean delivery in delivery room is an important guarantee of safe delivery.

摘要

目的

探讨剖宫产术后阴道试产(TOLAC)的可行性及安全性。

方法

回顾性分析广东省5家医疗中心2011年1月至2015年12月住院分娩信息,比较瘢痕子宫再次妊娠经阴道试产(研究组)与瘢痕妊娠(对照组)的妊娠结局,研究TOLAC的可行性及安全性。

结果

(1)2011 - 2015年,5家医疗中心共分娩95600例,其中子宫瘢痕妊娠13824例,包括12027例行择期再次剖宫产,1797例(13.00%,1797/13824)瘢痕子宫行阴道试产。在1308例阴道分娩中,试产成功率为72.79%(1308/1797)。2011年至2015年,剖宫产术后妊娠率呈上升趋势,分别为10.71%、13.28%、14.45%、15.54%和16.98%。阴道分娩意愿也在上升,分别为11.85%、12.25%、13.49%、13.82%和12.93%。(2)试产过程中瘢痕子宫产妇急诊剖宫产489例(27.21%,489/1797),因“社会因素”要求剖宫产有68例,占比13.91%(68/489),与对照组(7.18%,206/2869)比较,差异有统计学意义(χ² = 27.356,P = 0.000)。产程中诊断为“先兆子宫破裂”11.86%(58/489),与对照组(1.43%,41/2869)比较,差异有统计学意义(χ² = 1578.223,P = 0.000)。(3)研究组子宫破裂发生率(0.74%,9/1211)明显高于对照组(0.01%,2/31200;χ²>2000,P = 0.000)。研究组产后出血发生率为6.94%(84/1211),与对照组(3.05%,951/31200)比较,差异有统计学意义(χ² = 16.328,P = 0.000)。两组产程时限、重度窒息发生率及新生儿平均出生体重差异无统计学意义(P>0.05)。

结论

剖宫产术后妊娠率逐年上升,阴道分娩意愿增加,但总体仍较低。TOLAC安全可行,但风险也明显较高,严格产程监测并能在产房快速行剖宫产是安全分娩的重要保障。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验