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Modulation by estrogen and growth factors of transforming growth factor-alpha and epidermal growth factor receptor expression in normal and malignant human mammary epithelial cells.

作者信息

Salomon D S, Kidwell W R, Kim N, Ciardiello F, Bates S E, Valverius E, Lippman M E, Dickson R B, Stampfer M

机构信息

Laboratory of Tumor Immunology and Biology, National Cancer Institute, Bethesda, MD 20892.

出版信息

Recent Results Cancer Res. 1989;113:57-69. doi: 10.1007/978-3-642-83638-1_8.

DOI:10.1007/978-3-642-83638-1_8
PMID:2756237
Abstract
摘要

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The oestrogen-like effect of 4-hydroxytamoxifen on induction of transforming growth factor alpha mRNA in MDA-MB-231 breast cancer cells stably expressing the oestrogen receptor.4-羟基他莫昔芬对稳定表达雌激素受体的MDA-MB-231乳腺癌细胞中转化生长因子α mRNA诱导的雌激素样作用。
Br J Cancer. 1998 Jun;77(11):1812-9. doi: 10.1038/bjc.1998.301.
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Hormone receptors and cathepsin D levels in human breast epithelial cells transformed by chemical carcinogens and c-Ha-ras transfection.化学致癌物和c-Ha-ras转染转化的人乳腺上皮细胞中的激素受体和组织蛋白酶D水平
Breast Cancer Res Treat. 1994 Feb;29(2):169-77. doi: 10.1007/BF00665678.
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Epidermal growth factor-related peptides in the pathogenesis of human breast cancer.
表皮生长因子相关肽在人类乳腺癌发病机制中的作用
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Breast Cancer Res Treat. 1995;33(2):103-14. doi: 10.1007/BF00682718.
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Transforming growth factor-alpha promotes mammary tumorigenesis through selective survival and growth of secretory epithelial cells.转化生长因子-α通过分泌性上皮细胞的选择性存活和生长促进乳腺肿瘤发生。
Am J Pathol. 1995 Oct;147(4):1081-96.
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A mutation in the epidermal growth factor receptor in waved-2 mice has a profound effect on receptor biochemistry that results in impaired lactation.波发-2小鼠表皮生长因子受体的突变对受体生物化学有深远影响，导致泌乳受损。
Proc Natl Acad Sci U S A. 1995 Feb 28;92(5):1465-9. doi: 10.1073/pnas.92.5.1465.